Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES | O14684 | 4/20 | 0.53 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.50 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.49 |
| ▸ | HIF1AN | Q9NWT6 | 7/20 | 0.49 |
| ▸ | ODC1 | P11926 | 1/20 | 0.49 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.47 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.47 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14606068 | 0.96 | PTGES (0.56) | PTGESALOX5PTPN1ABCG2HIF1AN | |
| SCHEMBL16694310 | 0.89 | ABCG2 (0.62) | PTPN1ABCG2HIF1ANODC1ABCB1 | |
| SCHEMBL16694311 | 0.89 | ABCG2 (0.62) | PTPN1ABCG2HIF1ANODC1ABCB1 | |
| SCHEMBL5599975 | 0.85 | ODC1 (0.65) | PTPN1ABCG2HIF1ANODC1 | |
| SCHEMBL16694689 | 0.85 | ABCG2 (0.62) | PTPN1ABCG2HIF1ANODC1ABCB1 | |
| SCHEMBL16694688 | 0.85 | ABCG2 (0.62) | PTPN1ABCG2HIF1ANODC1ABCB1 | |
| SCHEMBL19365857 | 0.83 | HIF1AN (0.65) | PTPN1ABCG2HIF1ANODC1 | |
| SCHEMBL16865501 | 0.83 | PTPN1 (0.57) | PTPN1ABCG2HIF1ANODC1ABCB1 | |
| SCHEMBL14606067 | 0.81 | ODC1 (0.68) | PTPN1ABCG2HIF1ANODC1 | |
| SCHEMBL16865503 | 0.80 | ODC1 (0.55) | PTPN1ABCG2HIF1ANODC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1764363-A2 | SUBSTITUTED ACETOPHENONEDERIVATIVES | Riemser Arzneimittel AG (DE) | 2007-03-21 | — | — | EP | claimed |