Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY12 | Q9H244 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | NSD2 | O96028 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | NEK2 | P51955 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.31 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4098314 | 0.94 | KDM4E (0.38) | P2RY12KDM4ESMN1; SMN2MEN1KMT2A | |
| SCHEMBL4103251 | 0.93 | KDM4E (0.39) | P2RY12KDM4ESMN1; SMN2MEN1KMT2A | |
| SCHEMBL4097530 | 0.84 | ELANE (0.39) | P2RY12KDM4ESMN1; SMN2LMNAHSD17B10 | |
| SCHEMBL4114821 | 0.81 | LMNA (0.41) | P2RY12KDM4ESMN1; SMN2MEN1KMT2A | |
| SCHEMBL4105130 | 0.81 | NEK2 (0.42) | P2RY12KDM4ESMN1; SMN2MEN1KMT2A | |
| SCHEMBL4097566 | 0.81 | KDM4E (0.41) | P2RY12KDM4ESMN1; SMN2MEN1KMT2A | |
| SCHEMBL4105089 | 0.80 | KDM4E (0.39) | P2RY12KDM4ESMN1; SMN2MEN1KMT2A | |
| SCHEMBL5448530 | 0.80 | KDM4E (0.41) | P2RY12KDM4ESMN1; SMN2MEN1KMT2A | |
| SCHEMBL27718480 | 0.79 | KDM4E (0.38) | P2RY12KDM4ESMN1; SMN2MEN1KMT2A | |
| SCHEMBL4098910 | 0.78 | KDM4E (0.37) | P2RY12KDM4ESMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006073361-A9 | NOVEL PYRIDINE COMPOUNDS | ASTRAZENECA AB (SE) | 2007-08-02 | — | — | WO | disclosed |