SCHEMBL560046

SCHEMBL560046

CCCCOC(=O)C=CC(=O)O[Si](c1ccccc1)(c1ccccc1)C(C)(C)C

nearest known ligand 0.51

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ATM Q13315 1/20 0.51
HCAR2 Q8TDS4 5/20 0.50
APP P05067 5/20 0.42
TSHR P16473 4/20 0.42
TDP1 Q9NUW8 2/20 0.42
L3MBTL1 Q9Y468 2/20 0.42
MAPT P10636 1/20 0.42
RAB9A P51151 1/20 0.42
NPSR1 Q6W5P4 1/20 0.42
CYP3A4 P08684 2/20 0.39
MAPK1 P28482 2/20 0.39
ALDH1A1 P00352 2/20 0.39
HPGD P15428 1/20 0.39
TP53 P04637 1/20 0.38
HSD17B10 Q99714 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL560045 1.00 ATM (0.51) ATMHCAR2APPTSHRTDP1
SCHEMBL560570 1.00 ATM (0.51) ATMHCAR2APPTSHRTDP1
SCHEMBL5973442 0.85 HCAR2 (0.37) HCAR2TSHRTDP1L3MBTL1MAPT
SCHEMBL5974325 0.85 HCAR2 (0.37) HCAR2TSHRTDP1L3MBTL1MAPT
SCHEMBL5973451 0.85 HCAR2 (0.37) HCAR2TSHRTDP1L3MBTL1MAPT
SCHEMBL6426852 0.81 ATM (0.53) ATMHCAR2APPTSHRTDP1
SCHEMBL6426854 0.81 ATM (0.53) ATMHCAR2APPTSHRTDP1
SCHEMBL6657278 0.81 ATM (0.53) ATMHCAR2APPTSHRTDP1
SCHEMBL560289 0.79 HCAR2 (0.41) HCAR2TSHRL3MBTL1MAPTNPSR1
SCHEMBL560290 0.79 HCAR2 (0.41) HCAR2TSHRL3MBTL1MAPTNPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 68 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7736634-B2 Process for the preparation of polyorganosilylated carboxylate monomers or polymers thereof SIGMA COATINGS B.V. (NL) 2010-06-15 US claimed
US-7595370-B2 Reacting cyclosiloxane with unsaturated organosilylated carboxylate monomer or copolymer under presence of catalyst; antifouling paints, marine systems PPG B.V. (NL) 2009-09-29 US claimed
US-20060142516-A1 Process for the preparation of polyorganosilylated carboxylate monomers or polymers thereof SIGMA COATINGS B.V. (NL) 2006-06-29 US claimed
EP-1539861-A1 PROCESS FOR THE PREPARATION OF POLYORGANOSILYLATED CARBOXYLATE MONOMERS OR POLYMERS THEREOF Sigmakalon Services B.V. (NL) 2005-06-15 EP claimed
WO-2004007591-A1 PROCESS FOR THE PREPARATION OF POLYORGANOSILYLATED CARBOXYLATE MONOMERS OR POLYMERS THEREOF SIGMAKALON SERVICES B.V. (NL) 2004-01-22 WO claimed
EP-1380611-A1 Process for the preparation of polyorganosilylated carboxylate monomers or polymers thereof SigmaKalon Group B.V. (NL) 2004-01-14 EP claimed
US-11884813-B2 Macromonomer copolymer, epoxy resin composition, adhesive, molding material, and cured product MITSUBISHI CHEMICAL CORPORATION (JP) 2024-01-30 US disclosed
CN-116635488-A Compounds, polymers and antifouling coating compositions 三菱化学株式会社 2023-08-22 CN disclosed
CN-112166162-B Antifouling coating composition 三菱化学株式会社 2022-06-28 CN disclosed
US-11279835-B2 Antifouling coating composition comprising novel carbon-based hydrolysable polymers HEMPEL A/S (DK) 2022-03-22 US disclosed
CN-108137760-B (meth) acrylic copolymer and method for producing same, polymer solution, polymer-containing composition, and antifouling paint composition 三菱化学株式会社 2022-03-15 CN disclosed
CN-107207819-B Antifouling coating composition 三菱化学株式会社 2021-06-22 CN disclosed
US-20210163758-A1 ANTIFOULING COATING COMPOSITION COMPRISING NOVEL CARBON-BASED HYDROLYSABLE POLYMERS HEMPEL A/S (DK) 2021-06-03 US disclosed
US-5767171-A A MARINE, HYDROLYZABLE, ANTIFOULING, PROTECTIVE COATING BASED ON A POLYMER OF A TRIALKYLSILYL (METH)ACRYLATE AND AN ALKYLOXYALKYL (METH)ACRYLATE; NONCRACKING; UNIFORM EROSION; ADHESION NOF CORPORATION (JP) 1998-06-16 US disclosed
EP-0714957-B1 Hydrolyzable self-polishing coating composition NOF CORP (JP) 1998-03-04 EP disclosed
EP-0646630-B1 Antifouling coating composition NOF CORP (JP) 1997-04-23 EP disclosed
CN-1128778-A Coating compositions NIPPON OIL CO LTD (JP) 1996-08-14 CN disclosed
EP-0714957-A1 Hydrolyzable self-polishing coating composition NOF CORPORATION (JP) 1996-06-05 EP disclosed
US-5436284-A Preventing attachment of organisms to surfaces of structures submerged in seawater NOF CORPORATION (JP) 1995-07-25 US disclosed
EP-0646630-A1 Antifouling coating composition NOF CORPORATION (JP) 1995-04-05 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060142516-A1 Process for the preparation of polyorganosilylated carboxylate monomers or polymers thereof C1R, C9, PCBP1 ATM 2821/4885HCAR2 325/4885APP 4212/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.