SCHEMBL6426852

SCHEMBL6426852

CCCCOC(=O)/C=C\C(=O)O[Si](CCCC)(c1ccccc1)c1ccccc1

nearest known ligand 0.53

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ATM Q13315 1/20 0.53
HCAR2 Q8TDS4 5/20 0.51
TSHR P16473 4/20 0.43
TDP1 Q9NUW8 2/20 0.43
L3MBTL1 Q9Y468 2/20 0.43
APP P05067 5/20 0.43
MAPT P10636 1/20 0.43
RAB9A P51151 1/20 0.43
NPSR1 Q6W5P4 1/20 0.43
CYP3A4 P08684 2/20 0.40
MAPK1 P28482 2/20 0.40
ALDH1A1 P00352 2/20 0.40
ZDHHC2 Q9UIJ5 1/20 0.40
HPGD P15428 1/20 0.40
TP53 P04637 1/20 0.39
HSD17B10 Q99714 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6657278 1.00 ATM (0.53) ATMHCAR2TSHRTDP1L3MBTL1
SCHEMBL6426854 1.00 ATM (0.53) ATMHCAR2TSHRTDP1L3MBTL1
SCHEMBL6423035 0.86 ZDHHC2 (0.44) HCAR2TSHRMAPTALDH1A1ZDHHC2
SCHEMBL6423031 0.86 ZDHHC2 (0.44) HCAR2TSHRMAPTALDH1A1ZDHHC2
SCHEMBL6555334 0.81 ZDHHC2 (0.37) TSHRTDP1L3MBTL1NPSR1CYP3A4
SCHEMBL28852412 0.81 THRB (0.44) TSHRTDP1L3MBTL1ALDH1A1ZDHHC2
SCHEMBL560045 0.81 ATM (0.51) ATMHCAR2TSHRTDP1L3MBTL1
SCHEMBL560570 0.81 ATM (0.51) ATMHCAR2TSHRTDP1L3MBTL1
SCHEMBL560046 0.81 ATM (0.51) ATMHCAR2TSHRTDP1L3MBTL1
Benzene SCHEMBL28181570 0.78 ATM (0.87) ATMHCAR2TSHRTDP1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1539861-A1 PROCESS FOR THE PREPARATION OF POLYORGANOSILYLATED CARBOXYLATE MONOMERS OR POLYMERS THEREOF Sigmakalon Services B.V. (NL) 2005-06-15 EP claimed
WO-2004007591-A1 PROCESS FOR THE PREPARATION OF POLYORGANOSILYLATED CARBOXYLATE MONOMERS OR POLYMERS THEREOF SIGMAKALON SERVICES B.V. (NL) 2004-01-22 WO claimed
EP-3700985-A1 SELF-POLISHING ANTIFOULING COATING COMPOSITION COMPRISING ALKOXYSILANE Hempel A/S (DK) 2020-09-02 EP disclosed
CN-109952328-A (meth) acrylic copolymer, coating composition, coated article, and method for forming multilayer coating film 三菱化学株式会社 2019-06-28 CN disclosed
CN-107207819-A Antifouling coating composition 三菱化学株式会社 2017-09-26 CN disclosed