Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5601739 | 0.98 | MEN1 (0.32) | CA1CA2MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL5602476 | 0.87 | — | — | |
| Hydrochloric Acid SCHEMBL5601492 | 0.83 | — | — | |
| Hydrochloric Acid SCHEMBL5602265 | 0.81 | CA1 (0.39) | CA1CA2MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL5603083 | 0.81 | CA1 (0.33) | CA1CA2MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL5601200 | 0.79 | CA1 (0.40) | CA1CA2MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL5600976 | 0.79 | CA1 (0.32) | CA1CA2BACE1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL5601125 | 0.79 | CA1 (0.32) | CA1CA2BACE1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL5601332 | 0.79 | CA1 (0.33) | CA1CA2BACE1MEN1KMT2A | |
| Bromide SCHEMBL5603248 | 0.78 | CA1 (0.32) | CA1CA2BACE1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7276567-B2 | Heterocyclic substituted metallocene compounds for olefin polymerization | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2007-10-02 | — | — | US | disclosed |
| US-20050261449-A1 | Heterocyclic substituted metallocene compounds for olefin polymerization | EXXONMOBIL CHEMICAL PATENT INC. | 2005-11-24 | — | — | US | disclosed |