Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.44 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.44 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.44 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3597144 | 0.78 | SMN1; SMN2 (0.57) | GAAMAPTSMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL8246351 | 0.71 | GAA (0.49) | GAAMAPTSMN1; SMN2KDM4EHDAC3 | |
| SCHEMBL8245740 | 0.71 | HDAC3 (0.49) | GAAMAPTSMN1; SMN2KDM4EHDAC3 | |
| SCHEMBL3607234 | 0.70 | HDAC3 (0.45) | GAAMAPTSMN1; SMN2KDM4EHDAC3 | |
| SCHEMBL28366435 | 0.70 | GABRA5 (0.36) | GAAKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL8247957 | 0.70 | GAA (0.48) | GAAMAPTSMN1; SMN2KDM4EHDAC3 | |
| SCHEMBL11282184 | 0.69 | KMT2A (0.57) | GAAMAPTSMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL3608603 | 0.69 | HDAC3 (0.42) | GAAMAPTSMN1; SMN2KDM4EHDAC3 | |
| SCHEMBL23522646 | 0.68 | HDAC3 (0.46) | MAPTKDM4EHDAC3HDAC1HDAC2 | |
| SCHEMBL25248640 | 0.68 | HDAC3 (0.72) | HDAC3HDAC1HDAC2NCOR2HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007017728-A2 | NOVEL HETEROCYCLIC COMPOUNDS | ORCHID RESEARCH LABORATORIES LIMITED (IN) | 2007-02-15 | — | — | WO | claimed |
| WO-2007017728-A2 | NOVEL HETEROCYCLIC COMPOUNDS | ORCHID RESEARCH LABORATORIES LIMITED (IN) | 2007-02-15 | — | — | WO | disclosed |