SCHEMBL5600652

SCHEMBL5600652

Cc1c(C)n(C2=Cc3ccccc3C2[Zr](CCl)C2C(n3c(C)c(C)c4ccccc43)=Cc3ccccc32)c2ccccc12

nearest known ligand 0.32

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.32
MAPT P10636 2/20 0.31
CYP1A2 P05177 1/20 0.31
CYP3A4 P08684 1/20 0.31
CYP2D6 P10635 1/20 0.31
CYP2C19 P33261 1/20 0.31
ATM Q13315 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
ALDH1A1 P00352 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5603527 0.87 KDM4E (0.33) KDM4ECYP1A2CYP2C19ATM
SCHEMBL5600032 0.78 RXFP1 (0.32) MAPTCYP1A2CYP3A4CYP2D6CYP2C19
SCHEMBL5600120 0.77 ALDH1A1 (0.32) KDM4EMAPTCYP1A2CYP3A4CYP2D6
SCHEMBL5601754 0.77 CA1 (0.42) KDM4EMAPTALDH1A1
SCHEMBL5603936 0.76 KDM4E (0.31) KDM4EMAPTCYP1A2CYP3A4CYP2D6
Chloromethane SCHEMBL5600647 0.76 KDM4E (0.33) KDM4EMAPTCYP1A2CYP3A4CYP2D6
SCHEMBL5601278 0.76 KDM4E (0.31) KDM4EMAPTCYP1A2CYP3A4CYP2D6
Fluoride Ion SCHEMBL5601530 0.74 KDM4E (0.31) KDM4EMAPTCYP1A2CYP3A4CYP2D6
Bromide SCHEMBL5601721 0.74 KDM4E (0.31) KDM4EMAPTCYP1A2CYP3A4CYP2D6
Hydrochloric Acid SCHEMBL5601267 0.74 KDM4E (0.31) KDM4EMAPTCYP1A2CYP3A4CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7276567-B2 Heterocyclic substituted metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENTS INC. (US) 2007-10-02 US disclosed
US-20050261449-A1 Heterocyclic substituted metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENT INC. 2005-11-24 US disclosed