Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 5/20 | 0.37 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.36 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.35 |
| ▸ | TYR | P14679 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5603187 | 0.99 | LIPG (0.38) | TLR8LIPGCYP1A1TYRCYP3A4 | |
| SCHEMBL5601818 | 0.96 | TLR8 (0.35) | TLR8LIPGCYP1A1TYRCYP3A4 | |
| SCHEMBL5602904 | 0.87 | CYP1A1 (0.36) | TLR8CYP1A1MEN1KMT2AKDM4E | |
| SCHEMBL5600040 | 0.87 | KDM4E (0.33) | KDM4EALDH1A1GAAHPGD | |
| SCHEMBL5601327 | 0.87 | LIPG (0.41) | TLR8LIPGALOX5CYSLTR2CYSLTR1 | |
| SCHEMBL5603940 | 0.86 | CYP1A1 (0.38) | TLR8CYP1A1KDM4EALDH1A1HPGD | |
| SCHEMBL5600729 | 0.86 | CYP1A1 (0.38) | TLR8CYP1A1KDM4EALDH1A1HPGD | |
| SCHEMBL5601549 | 0.86 | CYP1A1 (0.38) | TLR8CYP1A1KDM4EALDH1A1HPGD | |
| SCHEMBL5603212 | 0.86 | CYP1A1 (0.38) | TLR8CYP1A1KDM4EALDH1A1HPGD | |
| SCHEMBL5599911 | 0.86 | CYP1A1 (0.38) | TLR8CYP1A1KDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7276567-B2 | Heterocyclic substituted metallocene compounds for olefin polymerization | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2007-10-02 | — | — | US | claimed |
| US-7276567-B2 | Heterocyclic substituted metallocene compounds for olefin polymerization | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2007-10-02 | — | — | US | disclosed |
| US-20050261449-A1 | Heterocyclic substituted metallocene compounds for olefin polymerization | EXXONMOBIL CHEMICAL PATENT INC. | 2005-11-24 | — | — | US | disclosed |