Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 3/20 | 0.35 |
| ▸ | GCGR | P47871 | 3/20 | 0.33 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.32 |
| ▸ | NOS2 | P35228 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5603679 | 0.95 | GCGR (0.38) | HSD11B1GCGRPTPN1KCNH2TDP1 | |
| SCHEMBL5602347 | 0.93 | KCNH2 (0.41) | HSD11B1GCGRPTPN1TLR8KCNH2 | |
| SCHEMBL5601934 | 0.93 | KCNH2 (0.41) | HSD11B1GCGRPTPN1TLR8KCNH2 | |
| SCHEMBL5601435 | 0.93 | KCNH2 (0.41) | HSD11B1GCGRPTPN1TLR8KCNH2 | |
| SCHEMBL5603031 | 0.93 | KCNH2 (0.41) | HSD11B1GCGRPTPN1TLR8KCNH2 | |
| SCHEMBL5600379 | 0.93 | KCNH2 (0.41) | HSD11B1GCGRPTPN1TLR8KCNH2 | |
| SCHEMBL5602833 | 0.93 | KCNH2 (0.41) | HSD11B1GCGRPTPN1TLR8KCNH2 | |
| SCHEMBL5601431 | 0.93 | KCNH2 (0.41) | HSD11B1GCGRPTPN1TLR8KCNH2 | |
| SCHEMBL5600666 | 0.89 | KDM4E (0.32) | GCGRKDM4EALDH1A1 | |
| SCHEMBL5603915 | 0.82 | TDP1 (0.33) | HSD11B1PSMB5KDM4EALDH1A1PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7276567-B2 | Heterocyclic substituted metallocene compounds for olefin polymerization | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2007-10-02 | — | — | US | claimed |
| US-7276567-B2 | Heterocyclic substituted metallocene compounds for olefin polymerization | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2007-10-02 | — | — | US | disclosed |
| US-20050261449-A1 | Heterocyclic substituted metallocene compounds for olefin polymerization | EXXONMOBIL CHEMICAL PATENT INC. | 2005-11-24 | — | — | US | disclosed |