SCHEMBL5600666

SCHEMBL5600666

CCCC1=C(C)c2ccccc2[N]1

nearest known ligand 0.35

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.32
ALDH1A1 P00352 1/20 0.32
GAA P10253 1/20 0.32
HPGD P15428 1/20 0.32
USP2 O75604 1/20 0.32
MAP2K7 O14733 1/20 0.31
S100A4 P26447 1/20 0.31
CDC25A P30304 1/20 0.31
CDC25B P30305 1/20 0.31
ELANE P08246 1/20 0.30
GCGR P47871 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5601003 0.89 HSD11B1 (0.35) KDM4EALDH1A1GCGR
SCHEMBL5603679 0.87 GCGR (0.38) GCGR
SCHEMBL5603031 0.86 KCNH2 (0.41) GCGR
SCHEMBL5600379 0.86 KCNH2 (0.41) GCGR
SCHEMBL5601431 0.86 KCNH2 (0.41) GCGR
SCHEMBL5601435 0.86 KCNH2 (0.41) GCGR
SCHEMBL5602833 0.86 KCNH2 (0.41) GCGR
SCHEMBL5601934 0.86 KCNH2 (0.41) GCGR
SCHEMBL5602347 0.86 KCNH2 (0.41) GCGR
SCHEMBL5602684 0.84 TP53 (0.36) ALDH1A1MAP2K7S100A4CDC25ACDC25B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7276567-B2 Heterocyclic substituted metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENTS INC. (US) 2007-10-02 US claimed
US-7276567-B2 Heterocyclic substituted metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENTS INC. (US) 2007-10-02 US disclosed
US-20050261449-A1 Heterocyclic substituted metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENT INC. 2005-11-24 US disclosed