Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 4/20 | 0.78 |
| ▸ | TRPA1 | O75762 | 3/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.56 |
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.48 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.48 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.48 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.48 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.48 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11548328 | 0.95 | MAOB (0.70) | MAOBTRPA1MAPK1ALDH1A1LMNA | |
| SCHEMBL11548324 | 0.95 | MAOB (0.70) | MAOBTRPA1MAPK1ALDH1A1LMNA | |
| SCHEMBL11548303 | 0.92 | MAOB (0.65) | MAOBTRPA1MAPK1ALDH1A1LMNA | |
| SCHEMBL11548292 | 0.92 | MAOB (0.65) | MAOBTRPA1MAPK1ALDH1A1LMNA | |
| SCHEMBL9246477 | 0.89 | MAOB (0.61) | MAOBTRPA1MAPK1ALDH1A1LMNA | |
| SCHEMBL23458007 | 0.88 | MAOB (1.00) | MAOBTRPA1MAPK1ALDH1A1LMNA | |
| SCHEMBL592744 | 0.88 | MAOB (1.00) | MAOBTRPA1MAPK1ALDH1A1LMNA | |
| SCHEMBL5875512 | 0.88 | MAOB (1.00) | MAOBTRPA1MAPK1ALDH1A1LMNA | |
| Benzene SCHEMBL135524 | 0.88 | MAOB (1.00) | MAOBTRPA1MAPK1ALDH1A1LMNA | |
| SCHEMBL6853572 | 0.88 | MAOB (1.00) | MAOBTRPA1MAPK1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1659990-A4 | LIGHT ADJUSTABLE LENSES CAPABLE OF POST-FABRICATION POWER MODIFICATION VIA MULTI-PHOTON PROCESSES | CALHOUN VISION (US) | 2007-09-26 | — | — | EP | disclosed |
| US-7237893-B2 | Light adjustable lenses capable of post-fabrication power modification via multi-photon processes | RXSIGHT, INC. | 2007-07-03 | — | — | US | disclosed |
| US-7074840-B2 | Light adjustable lenses capable of post-fabrication power modification via multi-photon processes | CALHOUN VISION (US) | 2006-07-11 | — | — | US | disclosed |
| EP-1659990-A2 | LIGHT ADJUSTABLE LENSES CAPABLE OF POST-FABRICATION POWER MODIFICATION VIA MULTI-PHOTON PROCESSES | Calhoun Vision (US) | 2006-05-31 | — | — | EP | disclosed |
| US-20060106126-A1 | Light adjustable lenses capable of post-fabrication power modification via multi-photon processes | CALHOUN VISION, INC (US) | 2006-05-18 | — | — | US | disclosed |
| WO-2005015268-A2 | LIGHT ADJUSTABLE LENSES CAPABLE OF POST-FABRICATION POWER MODIFICATION VIA MULTI-PHOTON PROCESSES | CALHOUN VISION (US) | 2005-02-17 | — | — | WO | disclosed |
| US-20050027031-A1 | Light adjustable lenses capable of post-fabrication power modification via multi-photon processes | RXSIGHT, INC. | 2005-02-03 | — | — | US | disclosed |