Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.70 |
| ▸ | NFE2L2 | Q16236 | 5/20 | 0.58 |
| ▸ | TRPA1 | O75762 | 3/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.52 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.45 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.45 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.45 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11548328 | 1.00 | MAOB (0.70) | MAOBNFE2L2TRPA1MAPK1ALDH1A1 | |
| SCHEMBL11548292 | 0.97 | MAOB (0.65) | MAOBNFE2L2TRPA1MAPK1ALDH1A1 | |
| SCHEMBL11548303 | 0.97 | MAOB (0.65) | MAOBNFE2L2TRPA1MAPK1ALDH1A1 | |
| SCHEMBL5601098 | 0.95 | MAOB (0.78) | MAOBNFE2L2TRPA1MAPK1ALDH1A1 | |
| SCHEMBL6360540 | 0.89 | NFE2L2 (0.68) | MAOBNFE2L2TRPA1CYP19A1MAOA | |
| SCHEMBL44502 | 0.89 | NFE2L2 (0.68) | MAOBNFE2L2TRPA1CYP19A1MAOA | |
| (Z)-1,2-Diphenylethene SCHEMBL7653150 | 0.89 | NFE2L2 (0.68) | MAOBNFE2L2TRPA1CYP19A1MAOA | |
| SCHEMBL44503 | 0.89 | NFE2L2 (0.68) | MAOBNFE2L2TRPA1CYP19A1MAOA | |
| SCHEMBL9540538 | 0.89 | NFE2L2 (0.68) | MAOBNFE2L2TRPA1CYP19A1MAOA | |
| SCHEMBL5411617 | 0.89 | NFE2L2 (0.68) | MAOBNFE2L2TRPA1CYP19A1MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4158099-A | FROM SCHIFF BASES AND BIPHENYL COMPOUND | CIBA-GEIGY AG (CH) | 1979-06-12 | — | — | US | disclosed |
| US-3991049-A | Aromatic compounds containing ethylene double bonds, processes for their manufacture and use | CIBA-GEIGY AG (CH) | 1976-11-09 | — | — | US | disclosed |