Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.42 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.34 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.33 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.33 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.33 |
| ▸ | LIPG | Q9Y5X9 | 2/20 | 0.33 |
| ▸ | LPL | P06858 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | DHFR | P00374 | 2/20 | 0.32 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5603581 | 1.00 | KCNH2 (0.42) | KCNH2GPR84TBXAS1CYSLTR2CYSLTR1 | |
| SCHEMBL5602689 | 1.00 | KCNH2 (0.42) | KCNH2GPR84TBXAS1CYSLTR2CYSLTR1 | |
| SCHEMBL5603834 | 1.00 | KCNH2 (0.42) | KCNH2GPR84TBXAS1CYSLTR2CYSLTR1 | |
| SCHEMBL5601266 | 1.00 | KCNH2 (0.42) | KCNH2GPR84TBXAS1CYSLTR2CYSLTR1 | |
| SCHEMBL5601446 | 1.00 | KCNH2 (0.42) | KCNH2GPR84TBXAS1CYSLTR2CYSLTR1 | |
| SCHEMBL5602892 | 1.00 | KCNH2 (0.42) | KCNH2GPR84TBXAS1CYSLTR2CYSLTR1 | |
| SCHEMBL5600761 | 0.98 | KCNH2 (0.40) | KCNH2GPR84TBXAS1CYSLTR2CYSLTR1 | |
| SCHEMBL5601012 | 0.94 | KCNH2 (0.33) | KCNH2TLR8 | |
| SCHEMBL5602787 | 0.84 | LIPG (0.42) | KCNH2LIPGTLR8 | |
| SCHEMBL5602726 | 0.83 | LIPG (0.40) | KCNH2LIPGTLR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7276567-B2 | Heterocyclic substituted metallocene compounds for olefin polymerization | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2007-10-02 | — | — | US | claimed |
| US-7276567-B2 | Heterocyclic substituted metallocene compounds for olefin polymerization | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2007-10-02 | — | — | US | disclosed |
| US-20050261449-A1 | Heterocyclic substituted metallocene compounds for olefin polymerization | EXXONMOBIL CHEMICAL PATENT INC. | 2005-11-24 | — | — | US | disclosed |