Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 7/20 | 0.36 |
| ▸ | MPEG1 | Q2M385 | 5/20 | 0.36 |
| ▸ | CDC25A | P30304 | 4/20 | 0.36 |
| ▸ | CDC25B | P30305 | 4/20 | 0.36 |
| ▸ | CDC25C | P30307 | 3/20 | 0.36 |
| ▸ | XIAP | P98170 | 2/20 | 0.36 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | PTGES | O14684 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5603008 | 1.00 | THRB (0.40) | THRBTSHRKCNH2ALDH1A1MAPT | |
| SCHEMBL5603001 | 1.00 | THRB (0.40) | THRBTSHRKCNH2ALDH1A1MAPT | |
| SCHEMBL5602439 | 1.00 | THRB (0.40) | THRBTSHRKCNH2ALDH1A1MAPT | |
| SCHEMBL5601662 | 1.00 | THRB (0.40) | THRBTSHRKCNH2ALDH1A1MAPT | |
| SCHEMBL5611684 | 0.78 | MEN1 (0.35) | KCNH2ALDH1A1KDM4EMEN1TP53 | |
| SCHEMBL17008157 | 0.66 | TSHR (0.57) | THRBTSHRKCNH2ALDH1A1KDM4E | |
| SCHEMBL31054446 | 0.65 | KCNH2 (0.50) | THRBTSHRKCNH2ALDH1A1HPGD | |
| SCHEMBL23854647 | 0.63 | TSHR (1.00) | THRBTSHRALDH1A1MEN1KMT2A | |
| Decane SCHEMBL23499900 | 0.63 | TSHR (1.00) | THRBTSHRALDH1A1MEN1KMT2A | |
| Dodecane SCHEMBL670207 | 0.63 | TSHR (1.00) | THRBTSHRALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7276567-B2 | Heterocyclic substituted metallocene compounds for olefin polymerization | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2007-10-02 | — | — | US | claimed |
| US-7276567-B2 | Heterocyclic substituted metallocene compounds for olefin polymerization | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2007-10-02 | — | — | US | disclosed |
| US-20050261449-A1 | Heterocyclic substituted metallocene compounds for olefin polymerization | EXXONMOBIL CHEMICAL PATENT INC. | 2005-11-24 | — | — | US | disclosed |