SCHEMBL5601666

SCHEMBL5601666

Cl[Hf](Cl)(C1C(n2c3c(c4ccccc42)CCCC3)=Cc2ccccc21)C1C(n2c3c(c4ccccc42)CCCC3)=Cc2ccccc21

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 3/20 0.44
CA2 P00918 3/20 0.44
HTR6 P50406 3/20 0.40
MEN1 O00255 3/20 0.38
KMT2A Q03164 3/20 0.38
KDM4E B2RXH2 3/20 0.38
GLA P06280 1/20 0.38
CASP1 P29466 1/20 0.38
CASP7 P55210 1/20 0.38
HSD17B10 Q99714 1/20 0.38
ALDH1A1 P00352 4/20 0.36
TSHR P16473 2/20 0.36
MAPT P10636 1/20 0.35
CHRM2 P08172 1/20 0.35
HTR1A P08908 1/20 0.35
CHRM5 P08912 1/20 0.35
ADRA2A P08913 1/20 0.35
DRD2 P14416 1/20 0.35
ADRA2B P18089 1/20 0.35
ADRA2C P18825 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5603395 0.93 CA1 (0.39) CA1CA2HTR6MEN1KMT2A
SCHEMBL5603955 0.89 CA1 (0.36) CA1CA2HTR6MEN1KMT2A
SCHEMBL5602401 0.89 CA1 (0.40) CA1CA2HTR6MEN1KMT2A
SCHEMBL5601174 0.89 CA1 (0.40) CA1CA2HTR6MEN1KMT2A
SCHEMBL5600873 0.89 CA1 (0.36) CA1CA2HTR6MEN1KMT2A
SCHEMBL5601142 0.87 CA1 (0.34) CA1CA2HTR6MEN1KMT2A
SCHEMBL5601213 0.83 CA1 (0.42) CA1CA2HTR6MEN1KMT2A
Fluoride SCHEMBL6064257 0.82 CA1 (0.41) CA1CA2HTR6MEN1KMT2A
SCHEMBL5599790 0.82 KDM4E (0.36) KDM4EL3MBTL1
Chloromethane SCHEMBL5601742 0.82 CA1 (0.41) CA1CA2HTR6MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7276567-B2 Heterocyclic substituted metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENTS INC. (US) 2007-10-02 US disclosed
US-20050261449-A1 Heterocyclic substituted metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENT INC. 2005-11-24 US disclosed