Chloromethane

Chloromethane

SCHEMBL5601742

C1=C(n2c3c(c4ccccc42)CCCC3)C([Zr]C2C(n3c4c(c5ccccc53)CCCC4)=Cc3ccccc32)c2ccccc21.CCl

nearest known ligand 0.41

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 3/20 0.41
CA2 P00918 3/20 0.41
HTR6 P50406 3/20 0.38
ALDH1A1 P00352 4/20 0.37
KDM4E B2RXH2 3/20 0.37
TSHR P16473 2/20 0.37
MEN1 O00255 3/20 0.36
KMT2A Q03164 3/20 0.36
MAPT P10636 1/20 0.36
GLA P06280 1/20 0.36
CASP1 P29466 1/20 0.36
CASP7 P55210 1/20 0.36
HSD17B10 Q99714 1/20 0.36
CHRM2 P08172 1/20 0.36
HTR1A P08908 1/20 0.36
CHRM5 P08912 1/20 0.36
ADRA2A P08913 1/20 0.36
DRD2 P14416 1/20 0.36
ADRA2B P18089 1/20 0.36
ADRA2C P18825 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Chloromethane SCHEMBL5600912 0.98 CA1 (0.40) CA1CA2HTR6ALDH1A1KDM4E
SCHEMBL5603771 0.89 CA1 (0.41) CA1CA2HTR6ALDH1A1KDM4E
SCHEMBL5603025 0.87 CA1 (0.40) CA1CA2HTR6ALDH1A1KDM4E
Chloromethane SCHEMBL5601328 0.85 CA1 (0.35) CA1CA2HTR6ALDH1A1KDM4E
Chloromethane SCHEMBL5600471 0.84 CA1 (0.41) CA1CA2HTR6ALDH1A1KDM4E
Chloromethane SCHEMBL6064733 0.83 CA1 (0.34) CA1CA2HTR6ALDH1A1KDM4E
Chloromethane SCHEMBL5603580 0.82 CA1 (0.34) CA1CA2HTR6ALDH1A1KDM4E
Chloromethane SCHEMBL5603517 0.82 KDM4E (0.34) KDM4EMAPT
SCHEMBL5601666 0.82 CA1 (0.44) CA1CA2HTR6ALDH1A1KDM4E
Chloromethane SCHEMBL5603605 0.81 CA1 (0.33) CA1CA2ALDH1A1KDM4ETSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7276567-B2 Heterocyclic substituted metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENTS INC. (US) 2007-10-02 US disclosed
US-20050261449-A1 Heterocyclic substituted metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENT INC. 2005-11-24 US disclosed