Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 8/20 | 0.45 |
| ▸ | MEN1 | O00255 | 7/20 | 0.45 |
| ▸ | MAPT | P10636 | 6/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | APAF1 | O14727 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | FNTA | P49354 | 1/20 | 0.41 |
| ▸ | FNTB | P49356 | 1/20 | 0.41 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | BLM | P54132 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL560186 | 1.00 | KMT2A (0.45) | KMT2AMEN1MAPTKDM4ESMN1; SMN2 | |
| SCHEMBL10088120 | 0.86 | KMT2A (0.49) | KMT2AMEN1MAPTKDM4ESMN1; SMN2 | |
| SCHEMBL12169853 | 0.86 | KMT2A (0.49) | KMT2AMEN1MAPTKDM4ESMN1; SMN2 | |
| SCHEMBL560223 | 0.86 | KMT2A (0.49) | KMT2AMEN1MAPTKDM4ESMN1; SMN2 | |
| SCHEMBL560022 | 0.86 | KMT2A (0.49) | KMT2AMEN1MAPTKDM4ESMN1; SMN2 | |
| SCHEMBL10088118 | 0.86 | KMT2A (0.49) | KMT2AMEN1MAPTKDM4ESMN1; SMN2 | |
| SCHEMBL13844616 | 0.86 | KMT2A (0.49) | KMT2AMEN1MAPTKDM4ESMN1; SMN2 | |
| SCHEMBL559736 | 0.86 | KMT2A (0.49) | KMT2AMEN1MAPTKDM4ESMN1; SMN2 | |
| SCHEMBL560222 | 0.86 | KMT2A (0.49) | KMT2AMEN1MAPTKDM4ESMN1; SMN2 | |
| SCHEMBL560021 | 0.86 | KMT2A (0.49) | KMT2AMEN1MAPTKDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120035373-A1 | PROCESSES OF PRODUCING GLUTAMIC ACID COMPOUNDS AND PRODUCTION INTERMEDIATES THEREFORE AND NOVEL INTERMEDIATE FOR THE PROCESSES | AJINOMOTO CO. INC (JP) | 2012-02-09 | — | — | US | disclosed |
| US-7868187-B2 | Processes of producing glutamic acid compounds and production intermediates therefore and novel intermediate for the processes | AJINOMOTO CO., INC. (JP) | 2011-01-11 | — | — | US | disclosed |
| US-20100105924-A1 | PROCESSES OF PRODUCING GLUTAMIC ACID COMPOUNDS AND PRODUCTION INTERMEDIATES THEREFORE AND NOVEL INTERMEDIATE FOR THE PROCESSES | AJINOMOTO CO. INC. (JP) | 2010-04-29 | — | — | US | disclosed |
| US-7678925-B2 | Processes of producing glutamic acid compounds and production intermediates therefore and novel intermediate for the processes | AJINOMOTO CO., INC. (JP) | 2010-03-16 | — | — | US | disclosed |
| US-20090259052-A1 | PROCESSES OF PRODUCING GLUTAMIC ACID COMPOUNDS AND PRODUCTION INTERMEDIATES THEREFORE AND NOVEL INTERMEDIATE FOR THE PROCESSES | AJINOMOTO CO. INC (JP) | 2009-10-15 | — | — | US | disclosed |
| US-7390909-B2 | Processes of producing glutamic acid compounds and production intermediates therefore and novel intermediate for the processes | AJINOMOTO CO., INC. (JP) | 2008-06-24 | — | — | US | disclosed |
| US-20080091032-A1 | PROCESSES OF PRODUCING GLUTAMIC ACID COMPOUNDS AND PRODUCTION INTERMEDIATES THEREFORE AND NOVEL INTERMEDIATE FOR THE PROCESSES | AJINOMOTO CO. INC (JP) | 2008-04-17 | — | — | US | disclosed |
| US-7064219-B2 | Processes of producing glutamic acid compounds and production intermediates therefore and novel intermediate for the processes | AJINOMOTO CO., INC. (JP) | 2006-06-20 | — | — | US | disclosed |
| US-20060074249-A1 | Processes of producing glutamic acid compounds and production intermediates therefore and novel intermediate for the processes | AJINOMOTO CO. INC (JP) | 2006-04-06 | — | — | US | disclosed |
| US-20050004394-A1 | Processes of producing glutamic acid compounds and production intermediates therefore and novel intermediate for the processes | AJINOMOTO CO. IN (JP) | 2005-01-06 | — | — | US | disclosed |
| EP-1466890-A1 | PROCESSES FOR THE PREPARATION OF GLUTAMIC ACID COMPOUNDS AND INTERMEDIATES THEREOF AND NOVEL INTERMEDIATES USED IN THE PROCESSES | Ajinomoto Co., Inc. (JP) | 2004-10-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120035373-A1 | PROCESSES OF PRODUCING GLUTAMIC ACID COMPOUNDS AND PRODUCTION INTERMEDIATES THEREFORE AND NOVEL INTERMEDIATE FOR THE PROCESSES | GLUL, MON2, GRIK5 | KMT2A 1562/4885MEN1 62/4885MAPT 1029/4885 |
| US-20050004394-A1 | Processes of producing glutamic acid compounds and production intermediates therefore and novel intermediate for the processes | GLUL, MON2, GRIK5 | KMT2A 1562/4885MEN1 62/4885MAPT 1029/4885 |
| US-20080091032-A1 | PROCESSES OF PRODUCING GLUTAMIC ACID COMPOUNDS AND PRODUCTION INTERMEDIATES THEREFORE AND NOVEL INTERMEDIATE FOR THE PROCESSES | GLUL, MON2, GRIK5 | KMT2A 1562/4885MEN1 62/4885MAPT 1029/4885 |
| US-20100105924-A1 | PROCESSES OF PRODUCING GLUTAMIC ACID COMPOUNDS AND PRODUCTION INTERMEDIATES THEREFORE AND NOVEL INTERMEDIATE FOR THE PROCESSES | GLUL, MON2, GRIK5 | KMT2A 1562/4885MEN1 62/4885MAPT 1029/4885 |
| US-20060074249-A1 | Processes of producing glutamic acid compounds and production intermediates therefore and novel intermediate for the processes | GLUL, MON2, GRIK5 | KMT2A 1562/4885MEN1 62/4885MAPT 1029/4885 |
| US-20090259052-A1 | PROCESSES OF PRODUCING GLUTAMIC ACID COMPOUNDS AND PRODUCTION INTERMEDIATES THEREFORE AND NOVEL INTERMEDIATE FOR THE PROCESSES | GLUL, MON2, GRIK5 | KMT2A 1562/4885MEN1 62/4885MAPT 1029/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.