Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.80 |
| ▸ | MAPT | P10636 | 2/20 | 0.76 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | CDC25B | P30305 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.45 |
| ▸ | DPP4 | P27487 | 1/20 | 0.44 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.44 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.44 |
| ▸ | GCGR | P47871 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1260172 | 0.86 | ALDH1A1 (0.80) | ALDH1A1MAPTKDM4ENPC1RAB9A | |
| SCHEMBL5599513 | 0.86 | ALDH1A1 (0.80) | ALDH1A1MAPTKDM4EKMT2ACHRNA7 | |
| SCHEMBL199471 | 0.86 | MAPT (1.00) | ALDH1A1MAPTKDM4ESMN1; SMN2KMT2A | |
| SCHEMBL5599197 | 0.83 | ALDH1A1 (0.60) | ALDH1A1MAPTMAPK1KDM4ESMN1; SMN2 | |
| SCHEMBL1258132 | 0.80 | MAPT (0.66) | ALDH1A1MAPTMAPK1KDM4EKMT2A | |
| SCHEMBL1260514 | 0.79 | MAPT (0.68) | ALDH1A1MAPTMAPK1KDM4ESMN1; SMN2 | |
| SCHEMBL1259728 | 0.76 | MAPT (0.71) | ALDH1A1MAPTMAPK1KDM4ESMN1; SMN2 | |
| SCHEMBL17495345 | 0.75 | MAPT (0.63) | ALDH1A1MAPTMAPK1KDM4ESMN1; SMN2 | |
| SCHEMBL5762071 | 0.74 | MAPK1 (0.65) | ALDH1A1MAPTMAPK1KDM4ESMN1; SMN2 | |
| SCHEMBL6272160 | 0.73 | ALDH1A1 (0.60) | ALDH1A1MAPTMAPK1KDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007026215-A1 | PYRAZOLE DERIVATIVES AS CANNABINOID RECEPTOR LIGANDS, PHARMACEUTICAL COMPOSITIONS CONTAINING? THEM, AND PROCESSES FOR THEIR PREPARATION | GLENMARK PHARMACEUTICALS S.A. (US) | 2007-03-08 | — | — | WO | disclosed |