Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 12/20 | 0.45 |
| ▸ | CA1 | P00915 | 10/20 | 0.45 |
| ▸ | CA9 | Q16790 | 9/20 | 0.45 |
| ▸ | CA12 | O43570 | 7/20 | 0.45 |
| ▸ | CA7 | P43166 | 4/20 | 0.43 |
| ▸ | NOTUM | Q6P988 | 7/20 | 0.40 |
| ▸ | CA6 | P23280 | 3/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.40 |
| ▸ | CA4 | P22748 | 2/20 | 0.40 |
| ▸ | CA5A | P35218 | 2/20 | 0.40 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5138813 | 0.86 | NOTUM (0.40) | CA2CA1CA9CA12CA7 | |
| SCHEMBL6430868 | 0.84 | CA2 (0.38) | CA2CA1CA9CA12CA7 | |
| SCHEMBL11127908 | 0.83 | MYC (0.47) | NOTUMCYP2C9 | |
| SCHEMBL5602626 | 0.80 | NOTUM (0.47) | NOTUMCYP2C9 | |
| SCHEMBL29484301 | 0.78 | MAPK1 (0.49) | CA2CA1CA9CA12CA7 | |
| SCHEMBL621024 | 0.78 | MAPK1 (0.49) | CA2CA1CA9CA12CA7 | |
| SCHEMBL1823138 | 0.78 | NOTUM (0.38) | CA2CA1CA9NOTUMCYP2C9 | |
| SCHEMBL6430865 | 0.77 | KDM4E (0.42) | — | |
| SCHEMBL4583701 | 0.77 | GAA (0.52) | CA2CA1CA9CA12CA7 | |
| SCHEMBL5138812 | 0.76 | CA1 (0.44) | CA2CA1CA9CA12CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022169755-A1 | SULFONAMIDE SUBSTITUTED N-(1H-INDOL-7-YL) BENZENESULFONAMIDES AND USES THEREOF | TRIANA BIOMEDICINES, INC. (US) | 2022-08-11 | — | — | WO | disclosed |
| WO-2007029076-A1 | ISOINDOLE DERIVATIVES AS ANTIMICROBIAL AGENTS | RANBAXY LABORATORIES LIMITED (IN) | 2007-03-15 | — | — | WO | disclosed |