Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | NOS2 | P35228 | 2/20 | 0.33 |
| ▸ | NOS3 | P29474 | 1/20 | 0.32 |
| ▸ | NOS1 | P29475 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.30 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
| ▸ | HTR2B | P41595 | 1/20 | 0.30 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5601130 | 0.97 | MAPT (0.39) | MAPTHPGDNOS2NOS1DRD2 | |
| SCHEMBL5600340 | 0.95 | MAPT (0.38) | MAPTHPGDNOS2NOS1HTR2A | |
| SCHEMBL5600716 | 0.95 | MAPT (0.38) | MAPTHPGDNOS2NOS1HTR2A | |
| SCHEMBL5602448 | 0.95 | MAPT (0.38) | MAPTHPGDNOS2NOS1HTR2A | |
| SCHEMBL5600361 | 0.95 | MAPT (0.38) | MAPTHPGDNOS2NOS1HTR2A | |
| SCHEMBL5600195 | 0.95 | MAPT (0.38) | MAPTHPGDNOS2NOS1HTR2A | |
| SCHEMBL5601869 | 0.95 | MAPT (0.38) | MAPTHPGDNOS2NOS1HTR2A | |
| SCHEMBL5602985 | 0.95 | MAPT (0.38) | MAPTHPGDNOS2NOS1HTR2A | |
| SCHEMBL5601216 | 0.93 | MAPT (0.31) | MAPTHPGDNOS2NOS3 | |
| SCHEMBL5604114 | 0.75 | NOS3 (0.32) | NOS2NOS3NOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7276567-B2 | Heterocyclic substituted metallocene compounds for olefin polymerization | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2007-10-02 | — | — | US | claimed |
| US-7276567-B2 | Heterocyclic substituted metallocene compounds for olefin polymerization | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2007-10-02 | — | — | US | disclosed |
| US-20050261449-A1 | Heterocyclic substituted metallocene compounds for olefin polymerization | EXXONMOBIL CHEMICAL PATENT INC. | 2005-11-24 | — | — | US | disclosed |