Chloromethane

Chloromethane

SCHEMBL5603517

C1=C(n2c3ccccc3c3ccccc32)C([Zr]C2C(n3c4ccccc4c4ccccc43)=Cc3ccccc32)c2ccccc21.CCl

nearest known ligand 0.34

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Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.34
ATM Q13315 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
GPR3 P46089 1/20 0.32
POLB P06746 1/20 0.32
LMNA P02545 1/20 0.30
MAPT P10636 1/20 0.30
HTT P42858 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Chloromethane SCHEMBL5600647 0.88 KDM4E (0.33) KDM4EATMMAPTHTT
SCHEMBL5603013 0.86 CYP19A1 (0.35) KDM4EATML3MBTL1
Chloromethane SCHEMBL5601742 0.82 CA1 (0.41) KDM4EMAPT
Chloromethane SCHEMBL5600912 0.82 CA1 (0.40) KDM4EMAPT
Chloromethane SCHEMBL5602109 0.80
Chloromethane SCHEMBL5600020 0.79 MAPT (0.33) MAPT
Chloromethane SCHEMBL5602946 0.78
SCHEMBL5602715 0.77 KDM4E (0.33) KDM4EATML3MBTL1MAPT
Chloromethane SCHEMBL5601719 0.76
Chloromethane SCHEMBL5599916 0.75 BIRC5 (0.39) MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7276567-B2 Heterocyclic substituted metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENTS INC. (US) 2007-10-02 US disclosed
US-20050261449-A1 Heterocyclic substituted metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENT INC. 2005-11-24 US disclosed