SCHEMBL5603522

SCHEMBL5603522

CC1=Cc2c(-c3ccccc3)cccc2C1(Cl)[Si](C)(C)C1(Cl)C(C)=Cc2c(-c3ccccc3)cccc21.[Zr]

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 2/20 0.33
ALDH1A1 P00352 2/20 0.33
RAB9A P51151 2/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
HPGD P15428 1/20 0.33
TSHR P16473 1/20 0.33
CYP1A2 P05177 2/20 0.33
CYP3A4 P08684 2/20 0.33
CYP2C9 P11712 2/20 0.33
CYP2C19 P33261 2/20 0.33
NPSR1 Q6W5P4 2/20 0.33
L3MBTL1 Q9Y468 2/20 0.33
HTT P42858 1/20 0.33
ADORA3 P0DMS8 1/20 0.33
ADORA2A P29274 1/20 0.33
ADORA1 P30542 1/20 0.33
SLC6A3 Q01959 1/20 0.32
ENPP3 O14638 1/20 0.32
ENPP1 P22413 1/20 0.32
PDCD1 Q15116 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27627844 0.81 PDCD1 (0.35) ALDH1A1HPGDCYP1A2CYP3A4CYP2C9
SCHEMBL27551823 0.80 PDCD1 (0.36) ALDH1A1HPGDCYP1A2CYP3A4CYP2C9
SCHEMBL27519768 0.78 PDCD1 (0.35) ALDH1A1HPGDCYP1A2CYP3A4CYP2C9
SCHEMBL217522 0.78 PDCD1 (0.36) PDCD1CD274CYP2A6
SCHEMBL218743 0.78 PDCD1 (0.36) TSHRPDCD1CD274CYP2A6
SCHEMBL217235 0.75 PDCD1 (0.36) PDCD1CD274CYP2A6
SCHEMBL5616230 0.75 PDCD1 (0.36) PDCD1CD274CYP2A6
SCHEMBL5616346 0.73 PDCD1 (0.32) PDCD1CD274CYP2A6
SCHEMBL28815102 0.73 PDCD1 (0.36) ALDH1A1HPGDNPSR1L3MBTL1ADORA3
SCHEMBL28947892 0.73 PDCD1 (0.36) ALDH1A1HPGDADORA3ADORA2AADORA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020101373-A1 SUPPORTED CATALYST FOR PROPYLENE POLYMERIZATION AND METHOD FOR PRODUCING POLYPROPYLENE RESIN USING SAME 롯데케미칼 주식회사 2020-05-22 WO disclosed
EP-1270602-B1 CATALYST FOR VINYL COMPOUND POLYMERIZATION AND PROCESS FOR PRODUCING VINYL POLYMER IDEMITSU KOSAN CO (JP) 2007-10-03 EP disclosed
US-6835788-B2 As polymerization catalyst IDEMITSU PETROCHEMICAL CO., LTD. (JP) 2004-12-28 US disclosed
US-20030027716-A1 Catalyst for vinyl compounds and process for production of vinyl polymers IDEMITSU KOSAN CO. LTD. (JP) 2003-02-06 US disclosed
EP-1270602-A1 CATALYST FOR VINYL COMPOUND POLYMERIZATION AND PROCESS FOR PRODUCING VINYL POLYMER IDEMITSU PETROCHEMICAL CO., LTD. (JP) 2003-01-02 EP disclosed
WO-2000034385-A9 MEL-BONDABLE POLYPROPYLENE/ETHYLENE POLYMER FIBER AND COMPOSITION FOR MAKING THE SAME DOW CHEMICAL CO (US) 2002-08-29 WO disclosed
EP-1179029-A1 FILM WITH ENHANCED PERFORMANCE PROPERTIES THE DOW CHEMICAL COMPANY (US) 2002-02-13 EP disclosed
EP-1159351-A1 MELT-BONDABLE POLYPROPYLENE/ETHYLENE POLYMER FIBER AND COMPOSITION FOR MAKING THE SAME THE DOW CHEMICAL COMPANY (US) 2001-12-05 EP disclosed
WO-2000066651-A1 FILM WITH ENHANCED PERFORMANCE PROPERTIES THE DOW CHEMICAL COMPANY (US) 2000-11-09 WO disclosed
WO-2000034385-A1 MEL-BONDABLE POLYPROPYLENE/ETHYLENE POLYMER FIBER AND COMPOSITION FOR MAKING THE SAME THE DOW CHEMICAL COMPANY (US) 2000-06-15 WO disclosed