SCHEMBL5603548

SCHEMBL5603548

CCCCCc1ccc2c(c1CCCCC)[N]c1ccccc1-2

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR3 P46089 1/20 0.38
NR1H2 P55055 1/20 0.38
NR1H3 Q13133 1/20 0.38
LIPG Q9Y5X9 1/20 0.37
ELANE P08246 3/20 0.36
CTSG P08311 2/20 0.36
TYR P14679 2/20 0.36
TLR8 Q9NR97 1/20 0.35
GCGR P47871 3/20 0.34
HSD11B1 P28845 2/20 0.34
PTPN1 P18031 1/20 0.33
MEN1 O00255 1/20 0.33
TP53 P04637 1/20 0.33
CYP3A4 P08684 1/20 0.33
ALOX5 P09917 1/20 0.33
MAPT P10636 1/20 0.33
ALOX15 P16050 1/20 0.33
TSHR P16473 1/20 0.33
HTT P42858 1/20 0.33
KMT2A Q03164 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5600551 0.99 GPR3 (0.40) GPR3NR1H2NR1H3LIPGELANE
SCHEMBL5602936 0.95 ELANE (0.35) GPR3NR1H2NR1H3LIPGELANE
SCHEMBL5601844 0.87 GPR3 (0.35) GPR3NR1H2NR1H3TLR8GCGR
SCHEMBL5603052 0.86 KDM4E (0.35) ELANECTSG
SCHEMBL5600511 0.85 GPR3 (0.38) GPR3NR1H2NR1H3LIPGTLR8
SCHEMBL5600994 0.85 GPR3 (0.38) GPR3NR1H2NR1H3LIPGTLR8
SCHEMBL5603226 0.85 GPR3 (0.38) GPR3NR1H2NR1H3LIPGTLR8
SCHEMBL5601229 0.85 GPR3 (0.38) GPR3NR1H2NR1H3LIPGTLR8
SCHEMBL5600998 0.85 GPR3 (0.38) GPR3NR1H2NR1H3LIPGTLR8
SCHEMBL5601851 0.85 GPR3 (0.38) GPR3NR1H2NR1H3LIPGTLR8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7276567-B2 Heterocyclic substituted metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENTS INC. (US) 2007-10-02 US claimed
US-7276567-B2 Heterocyclic substituted metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENTS INC. (US) 2007-10-02 US disclosed
US-20050261449-A1 Heterocyclic substituted metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENT INC. 2005-11-24 US disclosed