Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 3/20 | 0.60 |
| ▸ | RAF1 | P04049 | 17/20 | 0.59 |
| ▸ | BRAF | P15056 | 17/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4410085 | 0.97 | CSF1R (0.57) | CSF1RRAF1BRAF | |
| SCHEMBL4408515 | 0.96 | CSF1R (0.56) | CSF1RRAF1BRAF | |
| SCHEMBL4411100 | 0.95 | RAF1 (0.58) | CSF1RRAF1BRAF | |
| SCHEMBL4541529 | 0.90 | RAF1 (0.57) | CSF1RRAF1BRAF | |
| SCHEMBL5603594 | 0.89 | CSF1R (0.48) | CSF1RRAF1BRAF | |
| SCHEMBL4552241 | 0.86 | RAF1 (0.63) | CSF1RRAF1BRAF | |
| SCHEMBL5593491 | 0.86 | RAF1 (0.60) | CSF1RRAF1BRAF | |
| SCHEMBL5604230 | 0.86 | RAF1 (0.59) | CSF1RRAF1BRAF | |
| SCHEMBL4410928 | 0.83 | RIPK2 (0.48) | RAF1BRAF | |
| SCHEMBL4411709 | 0.82 | RIPK2 (0.47) | RAF1BRAF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007075896-A2 | HETEROCYCLIC CYTOKINE INHIBITORS | KEMIA, INC. (US) | 2007-07-05 | — | — | WO | disclosed |