Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAF1 | P04049 | 16/20 | 0.59 |
| ▸ | BRAF | P15056 | 16/20 | 0.59 |
| ▸ | CSF1R | P07333 | 4/20 | 0.56 |
| ▸ | LYN | P07948 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5604225 | 0.90 | BRAF (0.47) | RAF1BRAFCSF1RLYN | |
| SCHEMBL5593491 | 0.90 | RAF1 (0.60) | RAF1BRAFCSF1R | |
| SCHEMBL4411100 | 0.89 | RAF1 (0.58) | RAF1BRAFCSF1RLYN | |
| SCHEMBL4418487 | 0.88 | MAPK14 (0.48) | RAF1BRAFCSF1R | |
| SCHEMBL4552241 | 0.87 | RAF1 (0.63) | RAF1BRAFCSF1R | |
| SCHEMBL4565794 | 0.86 | CSF1R (0.60) | RAF1BRAFCSF1RLYN | |
| SCHEMBL5603601 | 0.86 | CSF1R (0.60) | RAF1BRAFCSF1R | |
| SCHEMBL4566569 | 0.86 | RAF1 (0.55) | RAF1BRAF | |
| SCHEMBL4412542 | 0.84 | RAF1 (0.54) | RAF1BRAF | |
| SCHEMBL4410085 | 0.83 | CSF1R (0.57) | RAF1BRAFCSF1RLYN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007075896-A2 | HETEROCYCLIC CYTOKINE INHIBITORS | KEMIA, INC. (US) | 2007-07-05 | — | — | WO | disclosed |