SCHEMBL5603675

SCHEMBL5603675

Cl[Hf](Cl)(C1C(n2cnnn2)=Cc2ccccc21)C1C(n2cnnn2)=Cc2ccccc21

nearest known ligand 0.40

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
NOTUM Q6P988 4/20 0.40
F2 P00734 1/20 0.35
ALDH1A1 P00352 4/20 0.35
NPSR1 Q6W5P4 1/20 0.35
KCNJ1 P48048 2/20 0.33
KMT2A Q03164 5/20 0.33
MAPT P10636 2/20 0.33
LMNA P02545 1/20 0.33
HTT P42858 1/20 0.33
HSD17B10 Q99714 1/20 0.31
MEN1 O00255 2/20 0.31
POLB P06746 1/20 0.31
CTDSP1 Q9GZU7 1/20 0.31
RAB9A P51151 1/20 0.30
KDM4E B2RXH2 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5602512 0.79
Hydrochloric Acid SCHEMBL5602869 0.78 NOTUM (0.41) NOTUMF2ALDH1A1NPSR1KCNJ1
SCHEMBL5602875 0.77 NOTUM (0.40) NOTUMF2ALDH1A1NPSR1KCNJ1
SCHEMBL5600543 0.77 NOTUM (0.40) NOTUMF2ALDH1A1NPSR1KCNJ1
SCHEMBL6064751 0.77 NOTUM (0.40) NOTUMF2ALDH1A1NPSR1KCNJ1
SCHEMBL5602509 0.77 KDM4E (0.33) ALDH1A1LMNAKDM4E
Hydrochloric Acid SCHEMBL5600537 0.77 NOTUM (0.42) NOTUMF2ALDH1A1NPSR1KCNJ1
Hydrochloric Acid SCHEMBL6064749 0.77 NOTUM (0.42) NOTUMF2ALDH1A1NPSR1KCNJ1
Hydrochloric Acid SCHEMBL5603671 0.75 NOTUM (0.41) NOTUMF2ALDH1A1NPSR1KCNJ1
SCHEMBL5603439 0.75

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7276567-B2 Heterocyclic substituted metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENTS INC. (US) 2007-10-02 US disclosed
US-20050261449-A1 Heterocyclic substituted metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENT INC. 2005-11-24 US disclosed