SCHEMBL5603987

SCHEMBL5603987

CCCCCc1ccc2c(c1CCCCC)N=N[N]2

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TYR P14679 3/20 0.38
CYP3A4 P08684 2/20 0.36
MAPT P10636 2/20 0.36
ALOX5 P09917 2/20 0.36
TDP1 Q9NUW8 2/20 0.36
MEN1 O00255 1/20 0.36
TP53 P04637 1/20 0.36
ALOX15 P16050 1/20 0.36
TSHR P16473 1/20 0.36
HTT P42858 1/20 0.36
KMT2A Q03164 1/20 0.36
LIPG Q9Y5X9 1/20 0.33
KCNH2 Q12809 1/20 0.33
TLR8 Q9NR97 1/20 0.32
KDM4E B2RXH2 1/20 0.31
USP2 O75604 1/20 0.31
ALDH1A1 P00352 1/20 0.31
GLA P06280 1/20 0.31
GAA P10253 1/20 0.31
HPGD P15428 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5602788 0.98 TYR (0.41) TYRCYP3A4MAPTALOX5TDP1
SCHEMBL5603901 0.95 TYR (0.35) TYRCYP3A4MAPTALOX5TDP1
SCHEMBL5602438 0.85 KCNH2 (0.33) CYP3A4TDP1TP53KCNH2TLR8
SCHEMBL5602884 0.85 KDM4E (0.34) KDM4EALDH1A1GAAHPGD
SCHEMBL5602173 0.84 KCNH2 (0.36) TYRCYP3A4ALOX5TDP1TP53
SCHEMBL5601355 0.84 KCNH2 (0.36) TYRCYP3A4ALOX5TDP1TP53
SCHEMBL5602256 0.84 KCNH2 (0.36) TYRCYP3A4ALOX5TDP1TP53
SCHEMBL5601744 0.84 KCNH2 (0.36) TYRCYP3A4ALOX5TDP1TP53
SCHEMBL5600627 0.84 KCNH2 (0.36) TYRCYP3A4ALOX5TDP1TP53
SCHEMBL5601285 0.84 KCNH2 (0.36) TYRCYP3A4ALOX5TDP1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7276567-B2 Heterocyclic substituted metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENTS INC. (US) 2007-10-02 US claimed
US-7276567-B2 Heterocyclic substituted metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENTS INC. (US) 2007-10-02 US disclosed
US-20050261449-A1 Heterocyclic substituted metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENT INC. 2005-11-24 US disclosed