Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 3/20 | 0.35 |
| ▸ | CTRC | Q99895 | 1/20 | 0.33 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 2/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5603987 | 0.95 | TYR (0.38) | TYRTLR8HTTMEN1TP53 | |
| SCHEMBL5602788 | 0.94 | TYR (0.41) | TYRTLR8HTTMEN1TP53 | |
| SCHEMBL5602884 | 0.86 | KDM4E (0.34) | HPGD | |
| SCHEMBL5603063 | 0.85 | NOS2 (0.32) | HTTNPC1HPGDMAPK1RAB9A | |
| SCHEMBL5602438 | 0.80 | KCNH2 (0.33) | TLR8TP53CYP3A4TDP1 | |
| SCHEMBL5601355 | 0.79 | KCNH2 (0.36) | TYRTLR8TP53CYP3A4ALOX5 | |
| SCHEMBL5601285 | 0.79 | KCNH2 (0.36) | TYRTLR8TP53CYP3A4ALOX5 | |
| SCHEMBL5602173 | 0.79 | KCNH2 (0.36) | TYRTLR8TP53CYP3A4ALOX5 | |
| SCHEMBL5600627 | 0.79 | KCNH2 (0.36) | TYRTLR8TP53CYP3A4ALOX5 | |
| SCHEMBL5602256 | 0.79 | KCNH2 (0.36) | TYRTLR8TP53CYP3A4ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7276567-B2 | Heterocyclic substituted metallocene compounds for olefin polymerization | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2007-10-02 | — | — | US | claimed |
| US-7276567-B2 | Heterocyclic substituted metallocene compounds for olefin polymerization | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2007-10-02 | — | — | US | disclosed |
| US-20050261449-A1 | Heterocyclic substituted metallocene compounds for olefin polymerization | EXXONMOBIL CHEMICAL PATENT INC. | 2005-11-24 | — | — | US | disclosed |