SCHEMBL560411

SCHEMBL560411

N[C@@H](CC(=O)OCC(=O)O)C(=O)OCC(=O)O

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PAM P19021 3/20 0.38
TSHR P16473 1/20 0.37
CTH P32929 1/20 0.37
CBS P35520 1/20 0.37
THPO P40225 1/20 0.37
THRB P10828 1/20 0.36
GRIK1 P39086 2/20 0.32
GRIK2 Q13002 2/20 0.32
GRM1 Q13255 2/20 0.32
GRM2 Q14416 2/20 0.32
GRM8 O00222 1/20 0.32
GRM6 O15303 1/20 0.32
GRIN2D O15399 1/20 0.32
GRIN3B O60391 1/20 0.32
GSR P00390 1/20 0.32
CYP1A2 P05177 1/20 0.32
GRM5 P41594 1/20 0.32
GRIA1 P42261 1/20 0.32
GRIA2 P42262 1/20 0.32
GRIA3 P42263 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2100343 1.00 PAM (0.38) PAMTSHRCTHCBSTHPO
SCHEMBL21067993 0.87 GRIK1 (0.43) PAMGRIK1GRIK2GRM1GRM2
SCHEMBL4317972 0.87 GRIK1 (0.43) PAMGRIK1GRIK2GRM1GRM2
SCHEMBL2100344 0.86 TSHR (0.40) PAMTSHRCTHCBSTHPO
SCHEMBL12723011 0.85 TSHR (0.41) PAMTSHRCTHCBSTHPO
SCHEMBL28462497 0.85 GRIK1 (0.42) PAMGRIK1GRIK2GRM1GRM2
SCHEMBL28980587 0.84 TSHR (0.39) PAMTSHRCTHCBSTHPO
SCHEMBL28980591 0.79 TSHR (0.34) TSHRCTHCBSTHPOTHRB
SCHEMBL7942268 0.79 PAM (0.44) PAMTSHRCTHCBSTHPO
SCHEMBL7942272 0.79 PAM (0.44) PAMTSHRCTHCBSTHPO

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 64 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118354755-A Use of specific carboxylic acids or salts thereof for repairing keratin fibres and/or preventing their breakage 欧莱雅 2024-07-16 CN claimed
CN-118179451-A Metal chelate chromatography medium and preparation method and application thereof 中国科学院过程工程研究所 2024-06-14 CN claimed
CN-116531804-A High ligand density metal chelating affinity chromatography medium and preparation method thereof 浙江大学衢州研究院 2023-08-04 CN claimed
CN-111215027-A Modification method of hydrothermal carbon microsphere chromatographic medium 中国科学院大连化学物理研究所 2020-06-02 CN claimed
CN-109576207-A A kind of separation method of the extracellular vesica based on metal ion network mixture 贺川江 2019-04-05 CN claimed
WO-2025080785-A1 METHODS AND MOLECULAR CONSTRUCTS FOR INCORPORATING MOLECULES INTO ELECTRICAL CIRCUITS ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) 2025-04-17 WO disclosed
CN-118354755-A Use of specific carboxylic acids or salts thereof for repairing keratin fibres and/or preventing their breakage 欧莱雅 2024-07-16 CN disclosed
CN-118340951-A Anti-adhesion material and surrogate biofilm using decellularized tissue 株式会社艾迪科 2024-07-16 CN disclosed
CN-118179451-A Metal chelate chromatography medium and preparation method and application thereof 中国科学院过程工程研究所 2024-06-14 CN disclosed
CN-113301989-B Water absorbing agent and method for producing water absorbing agent 株式会社日本触媒 2024-06-14 CN disclosed
CN-113272365-B Water absorbing agent containing water absorbing resin as main component and method for producing same 株式会社日本触媒 2024-05-10 CN disclosed
CN-117820145-A Synthesis process of metal chelating affinity filler ligand 常州天地人和生物科技有限公司 2024-04-05 CN disclosed
CN-1624122-A Recombinantly expressed carboxypeptidase b and purification thereof ROCHE DIAGNOSTICS GMBH (CH) 2005-06-08 CN disclosed
WO-2003087047-A1 METAL CHELATE COMPOSITION, MACROMOLECULE COMPLEX THEREOF, PREPARING METHOD THEREOF AND USE PEPTRON CO., LTD. (KR) 2003-10-23 WO disclosed
WO-2002037100-A2 NOVEL APPLICATIONS OF NICKEL NITRILOTRIACETIC ACID (NI-NTA) RESIN: HEMEPROTEIN REMOVAL, RECOVERY, AND PURIFICATION FROM BIOLOGICAL SAMPLES LYTTON SIMON D (DE) 2002-05-10 WO disclosed
US-6136580-A POLYPEPTIDE WITH ENZYMATIC ACTIVITY; FOR DIAGNOSIS, PREVENTION AND TREATMENT OF INFLAMMATION, TUMOR METASTASIS AND TISSUE REJECTION; ANTITUMOR AGENTS THE BURNHAM INSTITUTE (US) 2000-10-24 US disclosed
US-4258160-A BY USE OF A CATALYST COMPRISING A COBALT-CONTAINING COMPONENT, AN ALKYL ALUMINUM COMPONENT, AND CARBONYL SULFIDE THE FIRESTONE TIRE & RUBBER COMPANY (US) 1981-03-24 US disclosed
US-4248988-A CATALYST SYSTEM COMPRISING COBALT OR NICKEL COMPONENT, HYDROCARBYL ALUMINUM, AND HALOGENATED HYDROCARBON THE FIRESTONE TIRE & RUBBER COMPANY (US) 1981-02-03 US disclosed
US-4198496-A COBALT COMPONENT, MAGNESIUM OR MANGANESE CHLORIDE, IODIDE OR CARBOXYLIC ACID SATL, ORGANOALUMINUM HALIDE AS CATALYST THE FIRESTONE TIRE & RUBBER COMPANY (US) 1980-04-15 US disclosed
US-3993856-A CATALYST OF COBALT COMPOUND, HYDRO- OR HYDROCARBYLALUMINUM DIHALIDE, AND CARBON DISULFIDE THE FIRESTONE TIRE & RUBBER COMPANY (US) 1976-11-23 US disclosed