SCHEMBL5604212

SCHEMBL5604212

CC12OCCOC1CCCC2(CCCCCCCCCCO)S(=O)(=O)c1ccccc1

nearest known ligand 0.34

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
HTR7 P34969 8/20 0.34
GAA P10253 1/20 0.33
MCOLN3 Q8TDD5 1/20 0.33
HTR1A P08908 1/20 0.31
HTR2A P28223 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3387975 0.74 POLB (0.36) HTR7GAAMCOLN3
SCHEMBL7928278 0.71 HTR7 (0.36) HTR7GAAMCOLN3HTR1AHTR2A
SCHEMBL3392538 0.69 HTR7 (0.38) HTR7GAAMCOLN3HTR1AHTR2A
SCHEMBL3388921 0.68 HTR7 (0.35) HTR7GAAMCOLN3
SCHEMBL3392545 0.67 HTR7 (0.46) HTR7GAAMCOLN3HTR1AHTR2A
SCHEMBL7931571 0.64 HTR7 (0.38) HTR7GAAMCOLN3HTR1AHTR2A
SCHEMBL7919939 0.63 HTR7 (0.43) HTR7GAAMCOLN3HTR1AHTR2A
SCHEMBL7213202 0.58 HTR7 (0.34) HTR7
SCHEMBL4613715 0.56 TSHR (0.42)
SCHEMBL13254523 0.56 GAA (0.35) HTR7GAAMCOLN3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101180041-B Therapeutic agent for sensory disorder MEIJI DAIRIES CORP 2011-04-13 CN disclosed
CN-101180041-A Therapeutic agent for sensory disorder MEIJI DAIRIES CORP (JP) 2008-05-14 CN disclosed
US-7166642-B1 Use of cyclohexenone long-chain alcohol for treating neurodegenerative diseases MEIJI DAIRIES CORPORATION (JP) 2007-01-23 US disclosed
EP-1150667-B1 CYCLOHEXENONE LONG-CHAIN ALCOHOL FOR TREATING AMYOTROPHIC LATERAL SCLEROSIS MEIJI DAIRIES CORP (JP) 2004-07-14 EP disclosed
EP-1003706-B1 CYCLOHEXENONE LONG-CHAIN ALCOHOL AND MEDICAMENT CONTAINING SAME MEIJI MILK PROD CO LTD (JP) 2003-03-05 EP disclosed
EP-1150667-A1 CYCLOHEXENONE LONG-CHAIN ALCOHOL FOR TREATING AMYOTROPHIC LATERAL SCLEROSIS Meiji Dairies Corporation (JP) 2001-11-07 EP disclosed
US-6228893-B1 TREATING DEMENTIA MEIJI MILK PRODUCTS CO., LTD. (JP) 2001-05-08 US disclosed
WO-2000047199-A1 USE OF A CYCLOHEXENONE LONG-CHAIN ALCOHOL FOR TREATING NEURODEGENERATIVE DISEASES MEIJI DAIRIES CORPORATION (JP) 2000-08-17 WO disclosed
EP-1003706-A1 CYCLOHEXENONE LONG-CHAIN ALCOHOL AND MEDICAMENT CONTAINING SAME MEIJI MILK PRODUCTS COMPANY LIMITED (JP) 2000-05-31 EP disclosed
WO-1999008987-A1 CYCLOHEXENONE LONG-CHAIN ALCOHOL AND MEDICAMENT CONTAINING SAME MEIJI MILK PRODUCTS CO., LTD. (JP) 1999-02-25 WO disclosed