Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAF1 | P04049 | 7/20 | 0.38 |
| ▸ | BRAF | P15056 | 6/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.33 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.33 |
| ▸ | ACKR3 | P25106 | 5/20 | 0.32 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.32 |
| ▸ | CSGALNACT1 | Q8TDX6 | 1/20 | 0.32 |
| ▸ | SETD2 | Q9BYW2 | 2/20 | 0.32 |
| ▸ | NSD2 | O96028 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4418742 | 0.90 | RAF1 (0.45) | RAF1BRAFMAPK14 | |
| SCHEMBL4551600 | 0.88 | RAF1 (0.39) | RAF1BRAFRAB9ANPC1MAPK14 | |
| SCHEMBL4551892 | 0.85 | RAF1 (0.44) | RAF1BRAFMAPK14 | |
| SCHEMBL4552281 | 0.81 | RAF1 (0.45) | RAF1BRAFMAPK14 | |
| SCHEMBL4416244 | 0.81 | RAF1 (0.44) | RAF1BRAFMAPK14 | |
| SCHEMBL4551200 | 0.80 | CSGALNACT1 (0.44) | RAF1BRAFRAB9ANPC1CSGALNACT1 | |
| SCHEMBL4552240 | 0.79 | RAF1 (0.50) | RAF1BRAF | |
| SCHEMBL5593431 | 0.78 | RAF1 (0.49) | RAF1BRAFMAPK14 | |
| SCHEMBL5603875 | 0.77 | NAMPT (0.41) | RAB9ANPC1 | |
| SCHEMBL4551601 | 0.77 | RAF1 (0.48) | RAF1BRAFMAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007075896-A2 | HETEROCYCLIC CYTOKINE INHIBITORS | KEMIA, INC. (US) | 2007-07-05 | — | — | WO | disclosed |