Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAF1 | P04049 | 7/20 | 0.39 |
| ▸ | BRAF | P15056 | 7/20 | 0.39 |
| ▸ | SETD2 | Q9BYW2 | 2/20 | 0.35 |
| ▸ | CSGALNACT1 | Q8TDX6 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 6/20 | 0.33 |
| ▸ | PLAU | P00749 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4551892 | 0.89 | RAF1 (0.44) | RAF1BRAFMAPK14PLAU | |
| SCHEMBL4551601 | 0.89 | RAF1 (0.48) | RAF1BRAFMAPK14 | |
| SCHEMBL5604333 | 0.88 | RAF1 (0.38) | RAF1BRAFSETD2CSGALNACT1RAB9A | |
| SCHEMBL4552281 | 0.86 | RAF1 (0.45) | RAF1BRAFMAPK14PLAU | |
| SCHEMBL4552240 | 0.83 | RAF1 (0.50) | RAF1BRAF | |
| SCHEMBL5593431 | 0.82 | RAF1 (0.49) | RAF1BRAFMAPK14 | |
| SCHEMBL4551703 | 0.82 | MAPK14 (0.48) | RAF1BRAFMAPK14PLAU | |
| SCHEMBL4551200 | 0.81 | CSGALNACT1 (0.44) | RAF1BRAFCSGALNACT1RAB9ANPC1 | |
| SCHEMBL4565118 | 0.81 | RAF1 (0.56) | RAF1BRAFMAPK14 | |
| SCHEMBL4410286 | 0.81 | RAF1 (0.49) | RAF1BRAFMAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2035005-A2 | THERAPY USING CYTOKINE INHIBITORS | Kemia, INC. (US) | 2009-03-18 | — | — | EP | disclosed |
| WO-2007146712-A2 | THERAPY USING CYTOKINE INHIBITORS | KEMIA, INC. (US) | 2007-12-21 | — | — | WO | disclosed |