Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 15/20 | 0.64 |
| ▸ | ADORA1 | P30542 | 10/20 | 0.64 |
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.52 |
| ▸ | ADORA2B | P29275 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5024948 | 0.84 | ADORA2A (0.57) | ADORA2AADORA1ADORA3ADORA2BKMT2A | |
| SCHEMBL27661596 | 0.83 | ADORA2A (0.58) | ADORA2AADORA1ADORA3ADORA2BKMT2A | |
| SCHEMBL6038267 | 0.82 | ADORA2A (0.57) | ADORA2AADORA1ADORA3ADORA2BKMT2A | |
| SCHEMBL6038275 | 0.81 | ADORA2A (0.64) | ADORA2AADORA1ADORA3ADORA2BKMT2A | |
| SCHEMBL6038256 | 0.81 | ADORA2A (0.55) | ADORA2AADORA1ADORA3ADORA2BKMT2A | |
| SCHEMBL6038394 | 0.80 | ADORA2A (0.59) | ADORA2AADORA1ADORA3ADORA2BKMT2A | |
| SCHEMBL5024971 | 0.79 | ADORA2A (0.55) | ADORA2AADORA1ADORA3ADORA2BKMT2A | |
| SCHEMBL5022322 | 0.78 | ADORA2A (0.53) | ADORA2AADORA1ADORA3ADORA2BKMT2A | |
| SCHEMBL5022285 | 0.78 | ADORA2A (1.00) | ADORA2AADORA1ADORA3ADORA2BKMT2A | |
| SCHEMBL27681230 | 0.78 | ADORA2A (0.52) | ADORA2AADORA1ADORA3ADORA2BKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2007514003-A | — | — | 2007-05-31 | — | — | JP | claimed |
| EP-1697351-A1 | 2,6-BISHETEROARYL-4-AMINOPYRIMIDINES AS ADENOSINE RECEPTOR ANTAGONISTS | Almirall Prodesfarma AG (CH) | 2006-09-06 | — | — | EP | claimed |
| WO-2005058883-A1 | 2, 6 BISHETEROARYL-4-AMINOPYRIMIDINES AS ADENOSINE RECEPTOR ANTAGONISTS | ALMIRALL PRODESFARMA AG (CH) | 2005-06-30 | — | — | WO | claimed |
| EP-1697351-A1 | 2,6-BISHETEROARYL-4-AMINOPYRIMIDINES AS ADENOSINE RECEPTOR ANTAGONISTS | Almirall Prodesfarma AG (CH) | 2006-09-06 | — | — | EP | disclosed |
| WO-2005058883-A1 | 2, 6 BISHETEROARYL-4-AMINOPYRIMIDINES AS ADENOSINE RECEPTOR ANTAGONISTS | ALMIRALL PRODESFARMA AG (CH) | 2005-06-30 | — | — | WO | disclosed |