Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 20/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5509469 | 1.00 | REN (0.54) | REN | |
| SCHEMBL1866095 | 0.89 | REN (0.53) | REN | |
| SCHEMBL1866094 | 0.89 | REN (0.53) | REN | |
| SCHEMBL5508438 | 0.88 | REN (0.67) | REN | |
| SCHEMBL1865171 | 0.81 | REN (0.84) | REN | |
| SCHEMBL1863978 | 0.81 | REN (0.84) | REN | |
| SCHEMBL1863571 | 0.81 | REN (0.84) | REN | |
| SCHEMBL1863574 | 0.81 | REN (0.84) | REN | |
| SCHEMBL1861499 | 0.81 | REN (0.84) | REN | |
| SCHEMBL1861503 | 0.81 | REN (0.84) | REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007117560-A2 | PIPERIDINE AND MORPHOLINE RENIN INHIBITORS | VITAE PHARMACEUTICALS, INC. (US) | 2007-10-18 | — | — | WO | disclosed |