Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR3 | O14843 | 1/20 | 0.30 |
| ▸ | LCK | P06239 | 1/20 | 0.30 |
| ▸ | FYN | P06241 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5565070 | 0.89 | — | — | |
| Acetic Acid SCHEMBL6749754 | 0.72 | FFAR3 (0.37) | FFAR3LCKFYN | |
| SCHEMBL44788 | 0.71 | MAOA (0.32) | — | |
| SCHEMBL9158697 | 0.71 | — | — | |
| Acetic Acid SCHEMBL27499384 | 0.70 | FFAR3 (0.35) | FFAR3LCKFYN | |
| Acetic Acid SCHEMBL7760498 | 0.70 | FFAR3 (0.30) | FFAR3LCKFYN | |
| SCHEMBL5969293 | 0.70 | — | — | |
| Acetic Acid SCHEMBL8466656 | 0.68 | FFAR3 (0.33) | FFAR3LCKFYN | |
| SCHEMBL9459241 | 0.68 | — | — | |
| Formaldehyde SCHEMBL10840621 | 0.68 | MAOA (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1311627-B1 | PROCESS FOR PRODUCING COATINGS USING SURFACE-ACCUMULATING PHOTOINITIATORS | CIBA SC HOLDING AG (CH) | 2007-04-25 | — | — | EP | disclosed |
| US-6906113-B2 | Surface-active photoinitiators | CIBA SPECIALTY CHEMICALS CORP. (US) | 2005-06-14 | — | — | US | disclosed |
| EP-1311627-A2 | PROCESS FOR PRODUCING COATINGS USING SURFACE-ACTIVE PHOTOINITIATORS | Ciba SC Holding AG (CH) | 2003-05-21 | — | — | EP | disclosed |
| EP-1309599-A1 | SURFACE-ACTIVE PHOTOINITIATORS | Ciba SC Holding AG (CH) | 2003-05-14 | — | — | EP | disclosed |
| WO-2002014439-A2 | PROCESS FOR PRODUCING COATINGS USING SURFACE-ACTIVE PHOTOINITIATORS | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2002-02-21 | — | — | WO | disclosed |
| WO-2002014326-A1 | SURFACE-ACTIVE PHOTOINITIATORS | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2002-02-21 | — | — | WO | disclosed |