Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 5/20 | 0.43 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.38 |
| ▸ | CYSLTR1 | Q9Y271 | 4/20 | 0.36 |
| ▸ | PIN1 | Q13526 | 2/20 | 0.35 |
| ▸ | CYSLTR2 | Q9NS75 | 3/20 | 0.34 |
| ▸ | FFAR2 | O15552 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7944211 | 0.80 | PTGER4 (0.36) | PTGER4PTGER2CYSLTR1PIN1CYSLTR2 | |
| SCHEMBL5075349 | 0.80 | PTGER4 (0.52) | PTGER4PTGER2 | |
| SCHEMBL5072194 | 0.66 | PTGER2 (0.39) | PTGER4PTGER2 | |
| SCHEMBL6558651 | 0.64 | PTGER3 (0.61) | PTGER4PTGER2 | |
| SCHEMBL5075346 | 0.64 | PTGER4 (0.46) | PTGER4CYSLTR1PIN1CYSLTR2FFAR2 | |
| SCHEMBL11711444 | 0.64 | PTGER2 (0.41) | PTGER4PTGER2 | |
| SCHEMBL7886844 | 0.64 | PTGER2 (0.41) | PTGER4PTGER2 | |
| SCHEMBL12827125 | 0.62 | CA12 (0.41) | CYSLTR1FFAR2 | |
| SCHEMBL6556634 | 0.61 | PTGER4 (0.55) | PTGER4PTGER2 | |
| SCHEMBL5617449 | 0.61 | TRPA1 (0.52) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7255984-B2 | Combination therapy for osteoporosis | PFIZER INC. (US) | 2007-08-14 | — | — | US | claimed |