SCHEMBL5604883

SCHEMBL5604883

COc1ccc(CCc2ccc(C=O)cc2)cc1

nearest known ligand 0.76

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.76
CYP2A6 P11509 1/20 0.76
TAAR1 Q96RJ0 1/20 0.53
NPC1 O15118 1/20 0.53
RAB9A P51151 1/20 0.53
TDP1 Q9NUW8 1/20 0.53
LMNA P02545 2/20 0.51
SMN1; SMN2 Q16637 2/20 0.51
MAPT P10636 1/20 0.51
HPGD P15428 1/20 0.51
F2RL1 P55085 1/20 0.50
TP53 P04637 1/20 0.50
CYP3A4 P08684 1/20 0.50
TSHR P16473 1/20 0.50
TUBB4A P04350 1/20 0.50
TUBB P07437 1/20 0.50
TUBA3C P0DPH7 1/20 0.50
TUBA1B P68363 1/20 0.50
TUBA4A P68366 1/20 0.50
TUBB4B P68371 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9607336 0.90 ALDH1A1 (0.79) ALDH1A1CYP2A6NPC1RAB9ATDP1
SCHEMBL2231514 0.88 ALDH1A1 (0.63) ALDH1A1CYP2A6TAAR1NPC1RAB9A
SCHEMBL2232493 0.88 ALDH1A1 (0.63) ALDH1A1CYP2A6TAAR1NPC1RAB9A
Anisaldehyde SCHEMBL717471 0.87 ALDH1A1 (1.00) ALDH1A1CYP2A6LMNATP53CYP3A4
Anisaldehyde SCHEMBL1100 0.87 ALDH1A1 (1.00) ALDH1A1CYP2A6LMNATP53CYP3A4
Anisaldehyde SCHEMBL1477047 0.85 ALDH1A1 (0.95) ALDH1A1CYP2A6LMNATP53CYP3A4
Anisaldehyde SCHEMBL31123393 0.85 ALDH1A1 (0.95) ALDH1A1CYP2A6LMNATP53CYP3A4
Anisaldehyde SCHEMBL28617892 0.85 ALDH1A1 (0.95) ALDH1A1CYP2A6LMNATP53CYP3A4
Anisaldehyde SCHEMBL1475478 0.85 ALDH1A1 (0.95) ALDH1A1CYP2A6LMNATP53CYP3A4
Anisaldehyde SCHEMBL11255570 0.85 ALDH1A1 (0.95) ALDH1A1CYP2A6LMNATP53CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9795140-B2 Molecules having pesticidal utility, and intermediates, compositions, and processes, related thereto DOW AGROSCIENCES LLC (US) 2017-10-24 US disclosed
EP-1675813-B1 METHOD FOR PREPARING PARA-PHENYL ALKYNYL BENZALDEHYDES SERONO LAB (CH) 2007-12-19 EP disclosed
US-4371607-A 4-Halogeno-5-(halogenomethyl-phenyl)-oxazole derivatives, a process for the preparation thereof, and radiation-sensitive compositions containing these derivatives HOECHST AKTIENGESELLSCHAFT (DE) 1983-02-01 US disclosed
EP-0041675-A2 4-Halogen-5-(trichloromethyl-phenyl)-oxazole derivatives, process for preparing them and radiation-sensitive compositions containing them HOECHST AKTIENGESELLSCHAFT (DE) 1981-12-16 EP disclosed