SCHEMBL5605050

SCHEMBL5605050

Nc1ccc(N)c2c(Nc3ccccc3)ccc(Nc3ccccc3)c12

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 11/20 0.61
GAA P10253 11/20 0.61
ALDH1A1 P00352 10/20 0.61
KDM4E B2RXH2 9/20 0.61
MEN1 O00255 7/20 0.61
KMT2A Q03164 7/20 0.61
LMNA P02545 3/20 0.61
CYP1A2 P05177 2/20 0.61
CYP2C9 P11712 2/20 0.61
CYP2C19 P33261 2/20 0.61
CYP2D6 P10635 1/20 0.61
TDP1 Q9NUW8 6/20 0.52
ALOX15 P16050 4/20 0.52
HTT P42858 3/20 0.52
GFER P55789 3/20 0.51
HSD17B10 Q99714 5/20 0.50
HPGD P15428 5/20 0.50
L3MBTL1 Q9Y468 4/20 0.50
THRB P10828 1/20 0.50
ALOX12 P18054 2/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5605493 1.00 MAPT (0.61) MAPTGAAALDH1A1KDM4EMEN1
SCHEMBL8486840 0.79 MAPT (0.64) MAPTGAAALDH1A1KDM4EMEN1
SCHEMBL5146745 0.78 GAA (0.65) MAPTGAAALDH1A1KDM4EMEN1
SCHEMBL11793501 0.77 MAPT (0.55) MAPTGAAALDH1A1KDM4EMEN1
SCHEMBL2035899 0.77 GAA (0.55) MAPTGAAALDH1A1KDM4EMEN1
SCHEMBL29388147 0.76 MAPT (1.00) MAPTGAAALDH1A1KDM4EMEN1
SCHEMBL5084625 0.76 MAPT (0.67) MAPTGAAALDH1A1KDM4EMEN1
SCHEMBL217480 0.76 MAPT (1.00) MAPTGAAALDH1A1KDM4EMEN1
SCHEMBL9577793 0.75 MAPT (0.53) MAPTGAAALDH1A1KDM4EMEN1
Methane SCHEMBL4054340 0.74 MAPT (0.95) MAPTGAAALDH1A1KDM4EMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1462470-B1 Dielectric films and materials therefor DAICEL CHEM (JP) 2007-08-29 EP disclosed
US-20060241275-A1 Dielectric films and materials therefor NAGANO SHINYA 2006-10-26 US disclosed
US-7090925-B2 Dielectric films and materials therefor DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2006-08-15 US disclosed
US-20040192880-A1 Dielectric films and materials therefor DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2004-09-30 US disclosed
EP-1462470-A1 Dielectric films and materials therefor Daicel Chemical Industries, Ltd. (JP) 2004-09-29 EP disclosed