SCHEMBL2035899

SCHEMBL2035899

Cc1c(N)ccc(Nc2ccccc2)c1C

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 11/20 0.55
MAPT P10636 11/20 0.55
KDM4E B2RXH2 9/20 0.55
ALDH1A1 P00352 8/20 0.55
MEN1 O00255 5/20 0.55
KMT2A Q03164 5/20 0.55
CYP1A2 P05177 2/20 0.55
CYP2C9 P11712 2/20 0.55
CYP2C19 P33261 2/20 0.55
LMNA P02545 2/20 0.55
CYP2D6 P10635 1/20 0.55
HPGD P15428 4/20 0.50
HSD17B10 Q99714 4/20 0.50
THRB P10828 1/20 0.50
TDP1 Q9NUW8 5/20 0.48
GFER P55789 3/20 0.47
HTT P42858 3/20 0.47
ALOX15 P16050 3/20 0.47
L3MBTL1 Q9Y468 4/20 0.46
ALOX12 P18054 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30128772 0.79 GAA (0.50) GAAMAPTKDM4EALDH1A1MEN1
SCHEMBL15877078 0.79 GRM5 (0.42) MAPTMEN1KMT2ALMNANPC1
SCHEMBL6855456 0.78 MAPT (0.47) GAAMAPTKDM4EALDH1A1MEN1
SCHEMBL5605493 0.77 MAPT (0.61) GAAMAPTKDM4EALDH1A1MEN1
SCHEMBL5605050 0.77 MAPT (0.61) GAAMAPTKDM4EALDH1A1MEN1
SCHEMBL28292420 0.77 ALDH1A1 (0.46) GAAMAPTKDM4EALDH1A1MEN1
SCHEMBL599978 0.77 GAA (0.49) GAAMAPTKDM4EALDH1A1MEN1
SCHEMBL27512209 0.77 MAPT (0.43) GAAMAPTKDM4EALDH1A1MEN1
SCHEMBL28313595 0.77 MAPT (0.43) GAAMAPTKDM4EALDH1A1MEN1
SCHEMBL22169137 0.76 GAA (0.46) GAAMAPTKDM4EALDH1A1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11136535-B2 Leuco colorants as bluing agents in laundry care compositions THE PROCTER & GAMBLE COMPANY (US) 2021-10-05 US claimed
EP-3830232-A1 LEUCO COLORANTS AS BLUING AGENTS IN LAUNDRY CARE COMPOSITIONS The Procter & Gamble Company (US) 2021-06-09 EP claimed
US-20200032167-A1 STABILIZED COMPOSITIONS COMPRISING LEUCO COMPOUNDS MILLIKEN & COMPANY 2020-01-30 US claimed
WO-2020023812-A1 LEUCO COLORANTS AS BLUING AGENTS IN LAUNDRY CARE COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 2020-01-30 WO claimed
US-20200032173-A1 LEUCO COLORANTS AS BLUING AGENTS IN LAUNDRY CARE COMPOSITIONS THE PROCTER & GAMBLE COMPANY 2020-01-30 US claimed
US-20230392018-A1 COMPOSITIONS COMPRISING LEUCO COMPOUNDS AND COLORANTS MILLIKEN & COMPANY 2023-12-07 US disclosed
EP-4237498-A1 COMPOSITIONS COMPRISING LEUCO COMPOUNDS AND COLORANTS Milliken & Company (US) 2023-09-06 EP disclosed
WO-2022093189-A1 COMPOSITIONS COMPRISING LEUCO COMPOUNDS AND COLORANTS MILLIKEN & COMPANY (US) 2022-05-05 WO disclosed
US-11261403-B2 Stabilized compositions comprising leuco compounds MILLIKEN & COMPANY (US) 2022-03-01 US disclosed
US-11136535-B2 Leuco colorants as bluing agents in laundry care compositions THE PROCTER & GAMBLE COMPANY (US) 2021-10-05 US disclosed
EP-3830232-A1 LEUCO COLORANTS AS BLUING AGENTS IN LAUNDRY CARE COMPOSITIONS The Procter & Gamble Company (US) 2021-06-09 EP disclosed
WO-2020023812-A1 LEUCO COLORANTS AS BLUING AGENTS IN LAUNDRY CARE COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 2020-01-30 WO disclosed
CN-102630261-B A brass coated wire with a zinc gradient in the coating and its method for manufacturing BEKAERT CO 2015-04-01 CN disclosed
CN-104311787-A Preparation method and application of nano composite system modified polyurethane rubber with high abrasion resistance JIANGSU JESCI NEW MATERIAL TECHNOLOGY CO LTD 2015-01-28 CN disclosed
US-8822577-B2 Rubber composition for golf ball BRIDGESTONE SPORTS CO., LTD. (JP) 2014-09-02 US disclosed
US-20130131277-A1 RUBBER COMPOSITION FOR GOLF BALL BRIDGESTONE CORPORATION (JP) 2013-05-23 US disclosed
EP-2516729-A1 A BRASS COATED WIRE WITH A ZINC GRADIENT IN THE COATING AND ITS METHOD MANUFACTURING NV Bekaert SA (BE) 2012-10-31 EP disclosed
CN-102630261-A A brass coated wire with a zinc gradient in the coating and its method manufacturing BEKAERT SA NV 2012-08-08 CN disclosed
WO-2011076746-A1 A BRASS COATED WIRE WITH A ZINC GRADIENT IN THE COATING AND ITS METHOD MANUFACTURING NV BEKAERT SA (BE) 2011-06-30 WO disclosed
EP-0695780-B2 Rubber composition free of carcinogenic nitrosamine precursors and suitable as joining material MICHELIN & CIE (FR) 2006-12-27 EP disclosed