SCHEMBL560553

SCHEMBL560553

CC(=Cc1ccccc1)C(=O)F

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AKR1C3 P42330 1/20 0.69
ALDH1A1 P00352 2/20 0.52
TSHR P16473 1/20 0.52
HTT P42858 1/20 0.52
RAB9A P51151 4/20 0.49
SMN1; SMN2 Q16637 3/20 0.49
NPC1 O15118 2/20 0.49
DHODH Q02127 1/20 0.49
TRPM8 Q7Z2W7 1/20 0.49
RECQL P46063 1/20 0.48
MEN1 O00255 2/20 0.47
KMT2A Q03164 2/20 0.47
FBP1 P09467 1/20 0.47
GLA P06280 1/20 0.47
TDP1 Q9NUW8 1/20 0.47
PKM P14618 1/20 0.46
MAPK1 P28482 1/20 0.46
AKR1C1 Q04828 1/20 0.45
F2 P00734 1/20 0.45
GAA P10253 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16568719 0.82 AKR1C3 (1.00) AKR1C3ALDH1A1TSHRHTTRAB9A
SCHEMBL581982 0.82 AKR1C3 (1.00) AKR1C3ALDH1A1TSHRHTTRAB9A
SCHEMBL805622 0.82 AKR1C3 (0.75) AKR1C3ALDH1A1TSHRHTTRAB9A
SCHEMBL874087 0.82 AKR1C3 (0.75) AKR1C3ALDH1A1TSHRHTTRAB9A
SCHEMBL759655 0.82 AKR1C3 (0.75) AKR1C3ALDH1A1TSHRHTTRAB9A
SCHEMBL37034 0.82 AKR1C3 (1.00) AKR1C3ALDH1A1TSHRHTTRAB9A
SCHEMBL41906 0.82 AKR1C3 (1.00) AKR1C3ALDH1A1TSHRHTTRAB9A
SCHEMBL759656 0.82 AKR1C3 (0.75) AKR1C3ALDH1A1TSHRHTTRAB9A
SCHEMBL2532810 0.82 AKR1C3 (0.75) AKR1C3ALDH1A1TSHRHTTRAB9A
SCHEMBL23458002 0.81 AKR1C3 (0.73) AKR1C3ALDH1A1TSHRHTTRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7612145-B2 Composite material containing non-functional aromatic end group-containing polymer ROHM AND HAAS COMPANY (US) 2009-11-03 US claimed
EP-0745621-B1 Polymerisable composition based on thio(meth)acrylate monomer, transparent polymer compositions and their optical use ESSILOR INT (FR) 1998-04-15 EP claimed
EP-0745621-A1 Polymerisable composition based on thio(meth)acrylate monomer, transparent polymer compositions and their optional use ESSILOR INTERNATIONAL COMPAGNIE GENERALE D'OPTIQUE (FR) 1996-12-04 EP claimed
EP-1579521-B1 CURABLE COMPOSITION, CURED PRODUCT THEREOF, MOLDED PRODUCT THEREOF AND USE AS FUEL CELL SEPARATOR SHOWA DENKO KK (JP) 2018-04-11 EP disclosed
US-20160017076-A1 CURABLE COMPOSITION, TRANSPARENT HEAT-RESISTANT MATERIAL, AND USE THEREOF SHOWA DENKO K.K. (JP) 2016-01-21 US disclosed
US-8747703-B2 Electrically conducting curable resin composition, cured product thereof and method for producing the same SHOWA DENKO K.K. (JP) 2014-06-10 US disclosed
US-8609318-B2 Radiation-sensitive resin composition, method for forming resist pattern and polymer JSR CORPORATION (JP) 2013-12-17 US disclosed
US-8518524-B2 Transparent composite material SHOWA DENKO K.K. (JP) 2013-08-27 US disclosed
US-8460501-B2 Cured film and method for production thereof SHOWA DENKO K.K. (JP) 2013-06-11 US disclosed
US-8119039-B2 Transparent conductive substrate SHOWA DENKO K.K. (JP) 2012-02-21 US disclosed
US-20120034560-A1 RADIATION-SENSITIVE RESIN COMPOSITION, METHOD FOR FORMING RESIST PATTERN AND POLYMER JSR CORPORATION (JP) 2012-02-09 US disclosed
US-20080078976-A1 Composite material containing non-functional aromatic end group-containing polymer ROHM AND HAAS COMPANY 2008-04-03 US disclosed
US-7338730-B2 Conductive curable resin composition and separator for fuel cell SHOWA DENKO K.K. (JP) 2008-03-04 US disclosed
US-20060116466-A1 Curable composition, cured product thereof, molded product thereof and use as fuel cell separator SHOWA DENKO K.K. (JP) 2006-06-01 US disclosed
US-20050171270-A1 Conductive curable resin composition and separator for fuel cell SHOWA DENKO K.K. 2005-08-04 US disclosed
US-6472488-B2 MONOMERS CONTAIN THIO-CONTAINING HETEROCYCLES; USE IN MANUFACTURE OF WAVEGUIDES, OPTICAL FIBERS AND SPECTACLE LENSES ESSILOR INTERNATIONAL COMPAGNIE GENERALE D'OPTIQUE (FR) 2002-10-29 US disclosed
EP-0745621-B1 Polymerisable composition based on thio(meth)acrylate monomer, transparent polymer compositions and their optical use ESSILOR INT (FR) 1998-04-15 EP disclosed
EP-0745620-B1 Polymerisable compositions based on thio(meth)acrylate monomers, polymers having low yellowness index made from these compositions and ophthalmic lenses made therefrom ESSILOR INT (FR) 1997-10-29 EP disclosed
EP-0745621-A1 Polymerisable composition based on thio(meth)acrylate monomer, transparent polymer compositions and their optional use ESSILOR INTERNATIONAL COMPAGNIE GENERALE D'OPTIQUE (FR) 1996-12-04 EP disclosed
EP-0745620-A1 Polymerisable compositions based on thio(meth)acrylate monomers, polymers having low yellowness index made from these compositions and ophthalmic lenses made therefrom ESSILOR INTERNATIONAL COMPAGNIE GENERALE D'OPTIQUE (FR) 1996-12-04 EP disclosed