SCHEMBL5605591

SCHEMBL5605591

CCCC[Si](C)(C)C1CCCCO1

nearest known ligand 0.34

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 1/20 0.34
CNR1 P21554 3/20 0.34
CNR2 P34972 3/20 0.34
CYP1A2 P05177 1/20 0.33
SMN1; SMN2 Q16637 3/20 0.32
ALDH1A1 P00352 3/20 0.32
USP2 O75604 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
RAB9A P51151 1/20 0.31
HSD17B10 Q99714 1/20 0.31
PDE8B O95263 1/20 0.30
KDM4E B2RXH2 1/20 0.30
PKM P14618 1/20 0.30
HPGD P15428 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28629298 0.94 EPHX1 (0.37) EPHX1CNR1CNR2CYP1A2SMN1; SMN2
SCHEMBL28332148 0.93 EPHX1 (0.40) EPHX1CNR1CNR2CYP1A2SMN1; SMN2
SCHEMBL3769594 0.93 EPHX1 (0.40) EPHX1CNR1CNR2CYP1A2SMN1; SMN2
SCHEMBL8934882 0.93 EPHX1 (0.40) EPHX1CNR1CNR2CYP1A2SMN1; SMN2
SCHEMBL28379421 0.93 EPHX1 (0.40) EPHX1CNR1CNR2CYP1A2SMN1; SMN2
SCHEMBL2292980 0.93 EPHX1 (0.40) EPHX1CNR1CNR2CYP1A2SMN1; SMN2
SCHEMBL5499988 0.88 USP2 (0.30) SMN1; SMN2USP2
SCHEMBL11598764 0.85 EPHX1 (0.34) EPHX1CNR1CNR2CYP1A2ALDH1A1
SCHEMBL9254626 0.83 USP2 (0.34) SMN1; SMN2USP2HPGD
SCHEMBL1224499 0.83 USP2 (0.31) SMN1; SMN2USP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1763542-A2 TECHNIQUE FOR SELECTING POLYMERIZATION MODIFIERS CROSS REFERENCE STATEMENT Dow Gloval Technologies Inc. (US) 2007-03-21 EP claimed
WO-2006007094-A2 TECHNIQUE FOR SELECTING POLYMERIZATION MODIFIERS DOW GLOBAL TECHNOLOGIES INC. (US) 2006-01-19 WO claimed
CN-110204481-B Polysubstituted nitrogen-containing aromatic heterocyclic compound and preparation method and application thereof 中国农业大学 2021-01-19 CN disclosed
EP-1763542-A2 TECHNIQUE FOR SELECTING POLYMERIZATION MODIFIERS CROSS REFERENCE STATEMENT Dow Gloval Technologies Inc. (US) 2007-03-21 EP disclosed
WO-2006007094-A2 TECHNIQUE FOR SELECTING POLYMERIZATION MODIFIERS DOW GLOBAL TECHNOLOGIES INC. (US) 2006-01-19 WO disclosed
EP-0510631-B1 Siloxane modified polyester for fibre treatment DOW CORNING TORAY SILICONE (JP) 1996-07-03 EP disclosed
US-5417867-A Polyestersiloxane DOW CORNING TORAY SILICONE CO., LTD. (JP) 1995-05-23 US disclosed
EP-0400613-B1 Organopolysiloxane graft polyester and its manufacturing method DOW CORNING TORAY SILICONE (JP) 1994-03-02 EP disclosed
US-5290320-A Fiber treatment agent DOW CORNING TORAY SILICONE CO., LTD. (JP) 1994-03-01 US disclosed
US-5177160-A Organopolysiloxane graft polyester and its manufacturing method DOW CORNING TORAY SILICONE CO., LTD. (JP) 1993-01-05 US disclosed
EP-0510631-A1 Siloxane modified polyester for fibre treatment Dow Corning Toray Silicone Company, Limited (JP) 1992-10-28 EP disclosed
US-5082916-A ORGANOPOLYSILOXANE GRAFT POLYESTER AND ITS MANUFACTURING METHOD DOW CORNING TORAY SILICONE COMPANY, LTD. (JP) 1992-01-21 US disclosed
EP-0400613-A2 Organopolysiloxane graft polyester and its manufacturing method Dow Corning Toray Silicone Company Ltd. (JP) 1990-12-05 EP disclosed
US-4177176-A SHRINKPROOFING WOOL DOW CORNING LIMITED (GB) 1979-12-04 US disclosed
US-4098701-A CELLULOSE OR SYNTHETICS, WITH SILOXANES DOW CORNING LIMITED (GB) 1978-07-04 US disclosed
US-4098572-A SHRINKAGE INHIBITION DOW CORNING LIMITED (GB) 1978-07-04 US disclosed