SCHEMBL2292980

SCHEMBL2292980

CCCCCCCC[Si](C)(C)C1CCCCO1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 4/20 0.40
CNR1 P21554 4/20 0.37
CNR2 P34972 4/20 0.37
ALDH1A1 P00352 3/20 0.37
TDP1 Q9NUW8 1/20 0.37
NAAA Q02083 1/20 0.33
RAB9A P51151 2/20 0.32
SMN1; SMN2 Q16637 2/20 0.32
HSD17B10 Q99714 1/20 0.32
MEN1 O00255 1/20 0.32
NPC1 O15118 1/20 0.32
S1PR2 O95136 1/20 0.32
LMNA P02545 1/20 0.32
CYP1A2 P05177 1/20 0.32
POLB P06746 1/20 0.32
CYP3A4 P08684 1/20 0.32
CYP2D6 P10635 1/20 0.32
MAPT P10636 1/20 0.32
CYP2C9 P11712 1/20 0.32
CYP2C19 P33261 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3769594 1.00 EPHX1 (0.40) EPHX1CNR1CNR2ALDH1A1TDP1
SCHEMBL8934882 1.00 EPHX1 (0.40) EPHX1CNR1CNR2ALDH1A1TDP1
SCHEMBL28332148 1.00 EPHX1 (0.40) EPHX1CNR1CNR2ALDH1A1TDP1
SCHEMBL28379421 1.00 EPHX1 (0.40) EPHX1CNR1CNR2ALDH1A1TDP1
SCHEMBL28629298 0.98 EPHX1 (0.37) EPHX1CNR1CNR2ALDH1A1TDP1
SCHEMBL5605591 0.93 EPHX1 (0.34) EPHX1CNR1CNR2ALDH1A1TDP1
SCHEMBL28949837 0.86 EPHX1 (0.40) EPHX1CNR1CNR2ALDH1A1TDP1
SCHEMBL28605882 0.85 ALDH1A1 (0.36) EPHX1CNR1CNR2ALDH1A1TDP1
SCHEMBL5499988 0.85 USP2 (0.30) SMN1; SMN2
SCHEMBL28901503 0.84 SIGMAR1 (0.36)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9029057-B2 Single component developer composition XEROX CORPORATION (US) 2015-05-12 US claimed
US-20140315127-A1 Single Component Developer Composition XEROX CORPORATION (US) 2014-10-23 US claimed
US-9029057-B2 Single component developer composition XEROX CORPORATION (US) 2015-05-12 US disclosed
US-9029057-B2 Single component developer composition XEROX CORPORATION (US) 2015-05-12 US disclosed
US-20140315127-A1 Single Component Developer Composition XEROX CORPORATION (US) 2014-10-23 US disclosed
US-20140315127-A1 Single Component Developer Composition XEROX CORPORATION (US) 2014-10-23 US disclosed
US-8304568-B2 Organopolysiloxanes having polyhydroxyamido groups and preparation thereof WACKER CHEMIE AG (DE) 2012-11-06 US disclosed
US-20110190525-A1 ORGANOPOLYSILOXANES HAVING POLYHYDROXYAMIDO GROUPS AND PREPARATION THEREOF WACKER CHEMIE AG (DE) 2011-08-04 US disclosed
EP-1361915-A4 POROUS HYBRID PARTICLES WITH ORGANIC GROUPS REMOVED FROM THE SURFACE WATERS INVESTMENTS LTD (US) 2006-10-04 EP disclosed
WO-2005079427-A2 POROUS HYBRID MONOLITH MATERIALS WITH ORGANIC GROUPS REMOVED FROM THE SURFACE WATERS INVESTMENTS LIMITED (US) 2005-09-01 WO disclosed
EP-1361915-A1 POROUS HYBRID PARTICLES WITH ORGANIC GROUPS REMOVED FROM THE SURFACE Waters Investments Limited (US) 2003-11-19 EP disclosed
WO-2002060562-A1 POROUS HYBRID PARTICLES WITH ORGANIC GROUPS REMOVED FROM THE SURFACE WATERS INVESTMENTS LIMITED (US) 2002-08-08 WO disclosed
US-6093782-A MIXTURE COMPRISING AN ORGANOSILICON COMPOUND HAVING VINYL MOIETIES AND AN ORGANOSILICON COMPOUND HAVING SILICON-HYDROGEN MOIETIES, HYDROSILATION CATALYST, ROOM TEMPERATURE CROSSLINKING INHIBITOR; RELEASE AGENTS WACKER-CHEMIE GMBH (DE) 2000-07-25 US disclosed
US-3960810-A ORGANOSILOXANE POLYMER, CATALYST DOW CORNING LIMITED (WA) 1976-06-01 US disclosed