Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Diethylamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.55 |
| ▸ | USP2 | O75604 | 2/20 | 0.55 |
| ▸ | CASP1 | P29466 | 1/20 | 0.55 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.55 |
| ▸ | CASP7 | P55210 | 1/20 | 0.55 |
| ▸ | TERT | O14746 | 10/20 | 0.50 |
| ▸ | MAPT | P10636 | 6/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.50 |
| ▸ | EGFR | P00533 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | NSD2 | O96028 | 1/20 | 0.48 |
| ▸ | FGB | P02675 | 1/20 | 0.48 |
| ▸ | MMP14 | P50281 | 1/20 | 0.48 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6365841 | 0.89 | MEN1 (0.62) | MEN1KMT2AUSP2CASP1BRCA1 | |
| SCHEMBL8053208 | 0.88 | MAPT (0.66) | MEN1KMT2AUSP2CASP1BRCA1 | |
| SCHEMBL3055637 | 0.88 | MEN1 (0.57) | MEN1KMT2AUSP2CASP1BRCA1 | |
| SCHEMBL8698507 | 0.83 | MEN1 (0.55) | MEN1KMT2AUSP2CASP1BRCA1 | |
| SCHEMBL23616028 | 0.82 | MEN1 (0.51) | MEN1KMT2AUSP2CASP1BRCA1 | |
| Dimethylamine SCHEMBL5605716 | 0.78 | TERT (0.53) | MEN1KMT2AUSP2CASP1BRCA1 | |
| SCHEMBL11866966 | 0.78 | TERT (0.60) | MEN1KMT2AUSP2CASP1BRCA1 | |
| SCHEMBL11794571 | 0.77 | MAPT (0.49) | MEN1KMT2AUSP2CASP1BRCA1 | |
| SCHEMBL14876558 | 0.77 | TERT (0.59) | MEN1KMT2AUSP2CASP1BRCA1 | |
| SCHEMBL1304646 | 0.76 | TERT (0.62) | MEN1KMT2ATERTMAPTMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7202292-B2 | Colored polymeric resin composition with 1,8-diaminoanthraquinone derivative, article made therefrom, and method for making the same | GENERAL ELECTRIC COMPANY (US) | 2007-04-10 | — | — | US | claimed |