SCHEMBL5605839

SCHEMBL5605839

Nc1cc2cc(N)c(O)cc2cc1O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 9/20 0.46
GAA P10253 7/20 0.46
MAPT P10636 6/20 0.46
MEN1 O00255 5/20 0.46
KMT2A Q03164 5/20 0.46
KDM4E B2RXH2 4/20 0.46
PKM P14618 2/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
ALOX15 P16050 5/20 0.46
HSD17B10 Q99714 5/20 0.46
CYP3A4 P08684 2/20 0.46
ALOX12 P18054 3/20 0.42
HPGD P15428 2/20 0.42
SMN1; SMN2 Q16637 2/20 0.42
MAPK1 P28482 1/20 0.42
POLB P06746 1/20 0.40
RAB9A P51151 1/20 0.40
HTT P42858 2/20 0.37
RECQL P46063 2/20 0.37
USP2 O75604 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5606122 1.00 ALDH1A1 (0.46) ALDH1A1GAAMAPTMEN1KMT2A
SCHEMBL5605453 0.97 ALDH1A1 (0.44) ALDH1A1GAAMAPTMEN1KMT2A
SCHEMBL5604970 0.97 ALDH1A1 (0.44) ALDH1A1GAAMAPTMEN1KMT2A
SCHEMBL13732876 0.97 ALDH1A1 (0.44) ALDH1A1GAAMAPTMEN1KMT2A
SCHEMBL11251343 0.87 HSD17B10 (0.44) ALDH1A1GAAMAPTMEN1KMT2A
SCHEMBL11098377 0.87 ALDH1A1 (0.44) ALDH1A1GAAMAPTMEN1KMT2A
SCHEMBL140478 0.83 IDO1 (0.50) ALDH1A1GAAMAPTMEN1KMT2A
SCHEMBL8006577 0.83 IDO1 (0.50) ALDH1A1GAAMAPTMEN1KMT2A
SCHEMBL31328383 0.83 IDO1 (0.50) ALDH1A1GAAMAPTMEN1KMT2A
SCHEMBL29841101 0.83 IDO1 (0.50) ALDH1A1GAAMAPTMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2460852-B1 Crosslinkable composition and molded article made of same DAIKIN IND LTD (JP) 2014-03-26 EP disclosed
US-20140047976-A1 Cardo-Polybenzoxazole Polymer/Copolymer Membranes For Improved Permeability And Method For Fabricating The Same NATIONAL UNIVERSITY OF SINGAPORE (SG) 2014-02-20 US disclosed
WO-2012148360-A1 CARDO-POLYBENZOXAZOLE POLYMER/COPOLYMER MEMBRANES FOR IMPROVED PERMEABILITY AND METHOD FOR FABRICATING THE SAME NATIONAL UNIVERSITY OF SINGAPORE (SG) 2012-11-01 WO disclosed
EP-1462470-B1 Dielectric films and materials therefor DAICEL CHEM (JP) 2007-08-29 EP disclosed
US-20060241275-A1 Dielectric films and materials therefor NAGANO SHINYA 2006-10-26 US disclosed
US-7090925-B2 Dielectric films and materials therefor DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2006-08-15 US disclosed
US-20040192880-A1 Dielectric films and materials therefor DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2004-09-30 US disclosed
EP-1462470-A1 Dielectric films and materials therefor Daicel Chemical Industries, Ltd. (JP) 2004-09-29 EP disclosed
US-5534614-A Method for the preparation of amide oligomers and polybenzazole polymers therefrom THE DOW CHEMICAL COMPANY (US) 1996-07-09 US disclosed
US-5322916-A Method for the preparation of amide oligomers and polybenzazole polymers therefrom THE DOW CHEMICAL COMPANY (US) 1994-06-21 US disclosed
US-5011753-A Polyamides Containing Hexafluoroisopropylidene Groups Which May Be Cured To Form Polybenzoxazoles HOECHST CELANESE CORPORATION (US) 1991-04-30 US disclosed
US-4939215-A CHEMICAL AND RADIATION RESISTANCE; AIRCRAFT, ELECTRONICS HOECHST CELANESE CORPORATION (US) 1990-07-03 US disclosed
US-4845183-A MOLDING MATERIALS; FOR DIELECTRICS OR COATING SOLUTIONS; TOUGHNESS, FLEXIBILITY, TRANSPARENT HOECHST CELANESE CORPORATION (US) 1989-07-04 US disclosed
EP-0317942-A2 Heat resistant polyamides and polybenzoxazoles from bis-[(aminohydroxyphenyl hexafluoro-isopropyl] diphenyl ethers HOECHST CELANESE CORPORATION (US) 1989-05-31 EP disclosed