Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNAI3 | P08754 | 9/20 | 0.67 |
| ▸ | GNAI1 | P63096 | 9/20 | 0.67 |
| ▸ | GNAO1 | P09471 | 8/20 | 0.67 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10757141 | 1.00 | GNAI3 (0.67) | GNAI3GNAI1GNAO1L3MBTL1MEN1 | |
| SCHEMBL9427599 | 1.00 | GNAI3 (0.67) | GNAI3GNAI1GNAO1L3MBTL1MEN1 | |
| SCHEMBL10535735 | 1.00 | GNAI3 (0.67) | GNAI3GNAI1GNAO1L3MBTL1MEN1 | |
| SCHEMBL10535769 | 1.00 | GNAI3 (0.67) | GNAI3GNAI1GNAO1L3MBTL1MEN1 | |
| SCHEMBL10537382 | 1.00 | GNAI3 (0.67) | GNAI3GNAI1GNAO1L3MBTL1MEN1 | |
| SCHEMBL9428505 | 0.98 | GNAI3 (0.64) | GNAI3GNAI1GNAO1L3MBTL1MEN1 | |
| SCHEMBL9280678 | 0.93 | GNAI3 (0.57) | GNAI3GNAI1GNAO1L3MBTL1MEN1 | |
| SCHEMBL10525492 | 0.91 | GNAI3 (0.57) | GNAI3GNAI1GNAO1L3MBTL1KMT2A | |
| SCHEMBL4005891 | 0.90 | GNAI3 (0.59) | GNAI3GNAI1GNAO1L3MBTL1MEN1 | |
| SCHEMBL13772703 | 0.90 | GNAI3 (0.59) | GNAI3GNAI1GNAO1L3MBTL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7226990-B2 | Having one lipophilic substituent which is attached to the C-terminal amino acid; treatment of non-insulin dependent diabetes mellitus | NOVO NORDISK A/S (DK) | 2007-06-05 | — | — | US | disclosed |
| US-4837026-A | Transdermal and systemic preparation and method | THERAPEUTIC PATCH RESEARCH N.V. | 1989-06-06 | — | — | US | disclosed |
| EP-0240554-A1 | TRANSDERMAL AND SYSTEMIC PREPARATION AND METHOD | RAJADHYAKSHA, Vithal J. (US) | 1987-10-14 | — | — | EP | disclosed |
| WO-1987001935-A1 | TRANSDERMAL AND SYSTEMIC PREPARATION AND METHOD | RAJADHYAKSHA VITHAL J | 1987-04-09 | — | — | WO | disclosed |