Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 4/20 | 0.60 |
| ▸ | ESR1 | P03372 | 3/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.41 |
| ▸ | ACP3 | P15309 | 1/20 | 0.41 |
| ▸ | CTSC | P53634 | 3/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28919558 | 0.87 | ESR2 (0.56) | ESR2ESR1MEN1ALDH1A1CYP1A2 | |
| SCHEMBL1981578 | 0.87 | ESR2 (0.56) | ESR2ESR1MEN1ALDH1A1CYP1A2 | |
| SCHEMBL11788128 | 0.87 | ESR2 (0.56) | ESR2ESR1MEN1ALDH1A1CYP1A2 | |
| SCHEMBL6383255 | 0.87 | ESR2 (0.83) | ESR2ESR1MEN1ALDH1A1CYP1A2 | |
| SCHEMBL11018798 | 0.87 | ESR2 (0.56) | ESR2ESR1MEN1ALDH1A1CYP1A2 | |
| SCHEMBL10375928 | 0.87 | SLC6A4 (0.59) | ESR2ESR1MEN1ALDH1A1CYP1A2 | |
| SCHEMBL10569737 | 0.87 | ESR2 (0.56) | ESR2ESR1MEN1ALDH1A1CYP1A2 | |
| SCHEMBL5163915 | 0.87 | ESR2 (0.56) | ESR2ESR1MEN1ALDH1A1CYP1A2 | |
| SCHEMBL10564004 | 0.87 | ESR2 (0.56) | ESR2ESR1MEN1ALDH1A1CYP1A2 | |
| SCHEMBL28978055 | 0.87 | ESR2 (0.56) | ESR2ESR1MEN1ALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115974721-B | Method for synthesizing 2-carbonyl substituted nitrile compound through 2, 2-trifluoroethyl ketone | 平顶山学院 | 2024-07-02 | — | — | CN | claimed |
| CN-115974721-A | Method for synthesizing 2-carbonyl substituted nitrile compound through 2,2,2-trifluoroethyl ketone | 平顶山学院 | 2023-04-18 | — | — | CN | claimed |
| US-4071684-A | REACTING A NITRILE WITH A 2-AMINOETHYL HYDRAZINE; TRANSITION METAL SALT OR SULFUR CATALYST | THE DOW CHEMICAL COMPANY (US) | 1978-01-31 | — | — | US | claimed |
| JP-55028959-A | — | — | None | — | — | JP | disclosed |
| CN-119751305-B | Method for synthesizing 2, 3-diphenyl acrylonitrile compound by using benzyl cyanide compound through one-step method | 常州大学 | 2025-11-21 | — | — | CN | disclosed |
| CN-119923398-A | Cyclic compounds and methods of use thereof | 薛定谔公司 | 2025-05-02 | — | — | CN | disclosed |
| CN-119751305-A | Method for synthesizing 2, 3-diphenyl acrylonitrile compound by using benzyl cyanide compound through one-step method | 常州大学 | 2025-04-04 | — | — | CN | disclosed |
| CN-119751305-A | Method for synthesizing 2, 3-diphenyl acrylonitrile compound by using benzyl cyanide compound through one-step method | 常州大学 | 2025-04-04 | — | — | CN | disclosed |
| CN-115724891-B | Mn-L manganese complex and preparation method and application thereof | 浙江工业大学 | 2025-03-04 | — | — | CN | disclosed |
| CN-115974721-B | Method for synthesizing 2-carbonyl substituted nitrile compound through 2, 2-trifluoroethyl ketone | 平顶山学院 | 2024-07-02 | — | — | CN | disclosed |
| CN-115745718-B | Preparation method of delta-hydroxy substituted aromatic acetonitrile derivative | 浙江工业大学台州研究院 | 2024-02-13 | — | — | CN | disclosed |
| EP-0214793-B1 | (2-CYANO-2-ARYLETHYL)PYRIDINES, THEIR PREPARATION AND USE AS FUNGICIDES | ROHM AND HAAS COMPANY (US) | 1990-06-13 | — | — | EP | disclosed |
| US-4933339-A | PHYTOPATHOGENS | ROHM AND HAAS COMPANY (US) | 1990-06-12 | — | — | US | disclosed |
| EP-0214793-A1 | (2-Cyano-2-arylethyl)pyridines, their preparation and use as fungicides | ROHM AND HAAS COMPANY (US) | 1987-03-18 | — | — | EP | disclosed |
| US-4536599-A | HYDROLYZING THE NITRILE DERIVATIVE TO THE AMIDE USING AN ORGANIC QUATERNARY AMINE SALT CATALYST; EFFICIENCY | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1985-08-20 | — | — | US | disclosed |
| EP-0040896-B1 | SYNTHESIS OF AMIDES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1984-04-25 | — | — | EP | disclosed |
| EP-0040896-A2 | Synthesis of amides | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1981-12-02 | — | — | EP | disclosed |
| EP-0008532-A1 | Synthesis of amines | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1980-03-05 | — | — | EP | disclosed |
| JP-S5528959-A | PRODUCTION OF AMIDE DERIVATIVE | SUMITOMO CHEM CO LTD | 1980-02-29 | — | — | JP | disclosed |
| US-4071684-A | REACTING A NITRILE WITH A 2-AMINOETHYL HYDRAZINE; TRANSITION METAL SALT OR SULFUR CATALYST | THE DOW CHEMICAL COMPANY (US) | 1978-01-31 | — | — | US | disclosed |