SCHEMBL5606428

SCHEMBL5606428

CCOC(=O)C(NC(C)=O)(OCC)OCC

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PKM P14618 2/20 0.61
KDM4E B2RXH2 1/20 0.61
THRB P10828 2/20 0.59
HTT P42858 2/20 0.58
MAPT P10636 5/20 0.53
ATM Q13315 2/20 0.53
MEN1 O00255 2/20 0.53
KMT2A Q03164 2/20 0.53
L3MBTL1 Q9Y468 1/20 0.53
ALDH1A1 P00352 3/20 0.49
RECQL P46063 1/20 0.49
LMNA P02545 2/20 0.39
HSD17B10 Q99714 1/20 0.39
MGAM O43451 1/20 0.38
GAA P10253 1/20 0.38
SI P14410 1/20 0.38
MGAM2 Q2M2H8 1/20 0.38
SOAT1 P35610 1/20 0.38
TAAR1 Q96RJ0 2/20 0.38
TSHR P16473 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12064248 0.78 PKM (0.75) PKMKDM4ETHRBHTTMAPT
SCHEMBL10493815 0.75 PKM (0.60) PKMKDM4ETHRBHTTMAPT
SCHEMBL14593304 0.74 PKM (0.79) PKMKDM4ETHRBHTTMAPT
SCHEMBL12934291 0.74 PKM (0.70) PKMKDM4ETHRBHTTMAPT
SCHEMBL28125148 0.73 PKM (0.58) PKMKDM4ETHRBHTTMAPT
SCHEMBL1863608 0.73 PKM (0.68) PKMKDM4ETHRBHTTMAPT
SCHEMBL27299229 0.73 PKM (0.68) PKMKDM4ETHRBHTTMAPT
SCHEMBL7495628 0.72 PKM (0.56) PKMKDM4ETHRBHTTMAPT
SCHEMBL7334936 0.72 PKM (0.56) PKMKDM4ETHRBHTTMAPT
SCHEMBL14282806 0.72 PKM (0.66) PKMKDM4ETHRBHTTMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1817414-A1 VASOPRESSIN-BINDING L-NUCLEIC ACID Noxxon Pharma AG (DE) 2007-08-15 EP disclosed
WO-2006058705-A1 VASOPRESSIN-BINDING L-NUCLEIC ACID NOXXON PHARMA AG (DE) 2006-06-08 WO disclosed