Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | KCNN4 | O15554 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fluorobenzene SCHEMBL27288992 | 0.85 | NFE2L2 (0.48) | NFE2L2ALDH1A1CYP2A6TDP1MEN1 | |
| Fluorobenzene SCHEMBL27568171 | 0.84 | — | — | |
| Fluorobenzene SCHEMBL28258778 | 0.82 | NFE2L2 (0.46) | NFE2L2ALDH1A1CYP2A6TDP1MEN1 | |
| Fluorobenzene SCHEMBL29255955 | 0.82 | NFE2L2 (0.46) | NFE2L2ALDH1A1CYP2A6TDP1MEN1 | |
| Fluorobenzene SCHEMBL27300498 | 0.82 | NFE2L2 (0.46) | NFE2L2ALDH1A1CYP2A6TDP1MEN1 | |
| Fluorobenzene SCHEMBL25292684 | 0.82 | NFE2L2 (0.46) | NFE2L2ALDH1A1CYP2A6TDP1KCNN4 | |
| Fluorobenzene SCHEMBL7960137 | 0.82 | NFE2L2 (0.46) | NFE2L2ALDH1A1ACHELMNATSHR | |
| Fluorobenzene SCHEMBL3477245 | 0.81 | NFE2L2 (0.41) | NFE2L2ALDH1A1CYP2A6MEN1LMNA | |
| Fluorobenzene SCHEMBL27733550 | 0.81 | — | — | |
| Fluorobenzene SCHEMBL28081726 | 0.81 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105085439-B | A kind of preparation method of epoxiconazole intermediate | 江苏七洲绿色化工股份有限公司 | 2018-03-16 | — | — | CN | claimed |
| CN-107686475-A | 2,3,5 3 substituted thiophenes, derivative and its synthetic method | 湘潭大学 | 2018-02-13 | — | — | CN | claimed |
| CN-103819475-B | Synthetic method of sitagliptin and salt thereof | 浙江新和成股份有限公司 | 2017-04-19 | — | — | CN | claimed |
| CN-100488933-C | Method for the production of 2,3-cis-substituted 2-aryl propenals | BASF AG (DE) | 2009-05-20 | — | — | CN | claimed |
| CN-1894189-A | Process for preparing 2, 3-cis-substituted 2-arylpropenals | BASF AG (DE) | 2007-01-10 | — | — | CN | claimed |
| CN-110256404-A | Bifunctional vinyl compound, its preparation and purposes with insecticidal activity | 华东理工大学 | 2019-09-20 | — | — | CN | disclosed |
| CN-107686475-A | 2,3,5 3 substituted thiophenes, derivative and its synthetic method | 湘潭大学 | 2018-02-13 | — | — | CN | disclosed |
| CN-102947313-A | Pyripyropene derivative having acat2 inhibiting activity and stable to metabolizing enzymes | SCHOOL JURIDICAL PERSON KITASATO INST | 2013-02-27 | — | — | CN | disclosed |
| CN-102424686-A | Process for preparing high purity prasugrel hydrochloride | DAIICHI SANKYO CO LTD | 2012-04-25 | — | — | CN | disclosed |
| CN-102304014-A | Method for preparing epoxiconazole intermediate | JIANGSU SEVENCONTINENT GREEN CHEMICAL CO LTD | 2012-01-04 | — | — | CN | disclosed |
| CN-102026990-A | Novel inhibitors of hepatitis c virus replication | INTERMUNE INC | 2011-04-20 | — | — | CN | disclosed |
| CN-101675058-A | Process for preparing high purity prasugrel hydrochloride | DAIICHI SANKYO CO LTD | 2010-03-17 | — | — | CN | disclosed |
| US-6160030-A | High water content porous polymer | NOVARTIS AG (CH) | 2000-12-12 | — | — | US | disclosed |
| WO-2000015686-A1 | POLYMERS | NOVARTIS AG (CH) | 2000-03-23 | — | — | WO | disclosed |
| US-6015609-A | SOLUTION POLYMERIZABLE MIXTURES OF SOLVENT AND MONOMER TO FORM INTERPENETRATING NETWORK POLYMER THEN REMOVAL OF SOLVENT | NAVARTIS AG (CH) | 2000-01-18 | — | — | US | disclosed |
| EP-0889923-A1 | HIGH WATER CONTENT POROUS POLYMER | Novartis AG (CH) | 1999-01-13 | — | — | EP | disclosed |
| EP-0889924-A1 | PROCESS FOR MANUFACTURE OF A POROUS POLYMER FROM A MIXTURE | Novartis AG (CH) | 1999-01-13 | — | — | EP | disclosed |
| CN-1177343-A | Cell adhesion inhibitors | BIOGEN INC (US) | 1998-03-25 | — | — | CN | disclosed |
| WO-1997035906-A1 | HIGH WATER CONTENT POROUS POLYMER | NOVARTIS AG (CH) | 1997-10-02 | — | — | WO | disclosed |
| WO-1997035904-A1 | PROCESS FOR MANUFACTURE OF A POROUS POLYMER FROM A MIXTURE | NOVARTIS AG (CH) | 1997-10-02 | — | — | WO | disclosed |