Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9079473 | 0.74 | — | — | |
| Hydrochloric Acid SCHEMBL4300531 | 0.71 | — | — | |
| Hydrochloric Acid SCHEMBL818133 | 0.69 | — | — | |
| Hydrochloric Acid SCHEMBL6727289 | 0.68 | — | — | |
| Hydrochloric Acid SCHEMBL5513481 | 0.68 | — | — | |
| Hydrochloric Acid SCHEMBL6731846 | 0.67 | — | — | |
| Hydrochloric Acid SCHEMBL7945890 | 0.64 | — | — | |
| Hydrochloric Acid SCHEMBL8382533 | 0.64 | — | — | |
| Hydrochloric Acid SCHEMBL9421195 | 0.63 | — | — | |
| Hydrochloric Acid SCHEMBL3942645 | 0.61 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6489427-B1 | POLYETHYLENES ARE PREPARED HAVING A DENSITY IN THE RANGE 900-980 KG/M.SUP.3 AND A WEIGHT AVERAGE MOLECULAR WEIGHT .GTOREQ.375,000 CHARACTERIZED BY A FRACTURE TOUGHNESS AT -40.DEGREE. C. &GT;20 KJ/M.SUP.2 AND A DYNAMIC VISCOSITY FOR | BP CHEMICALS LIMITED (GB) | 2002-12-03 | — | — | US | claimed |
| EP-1080121-A1 | POLYMER COMPOSITIONS | BP Chemicals Limited (GB) | 2001-03-07 | — | — | EP | claimed |
| WO-1999048934-A1 | POLYMER COMPOSITIONS | BP CHEMICALS LIMITED (GB) | 1999-09-30 | — | — | WO | claimed |
| EP-1080121-B1 | Polyethylene and method of production thereof | INEOS EUROPE LTD (GB) | 2007-06-20 | — | — | EP | disclosed |
| US-6489427-B1 | POLYETHYLENES ARE PREPARED HAVING A DENSITY IN THE RANGE 900-980 KG/M.SUP.3 AND A WEIGHT AVERAGE MOLECULAR WEIGHT .GTOREQ.375,000 CHARACTERIZED BY A FRACTURE TOUGHNESS AT -40.DEGREE. C. &GT;20 KJ/M.SUP.2 AND A DYNAMIC VISCOSITY FOR | BP CHEMICALS LIMITED (GB) | 2002-12-03 | — | — | US | disclosed |
| EP-1080121-A1 | POLYMER COMPOSITIONS | BP Chemicals Limited (GB) | 2001-03-07 | — | — | EP | disclosed |
| WO-1999048934-A1 | POLYMER COMPOSITIONS | BP CHEMICALS LIMITED (GB) | 1999-09-30 | — | — | WO | disclosed |