Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA4 | P22748 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5607333 | 1.00 | CYP2D6 (0.65) | CYP2D6KDM4EALDH1A1SLC6A2SLC6A3 | |
| SCHEMBL5096916 | 1.00 | CYP2D6 (0.65) | CYP2D6KDM4EALDH1A1SLC6A2SLC6A3 | |
| SCHEMBL13465759 | 0.84 | CYP2D6 (0.65) | CYP2D6ALDH1A1SLC6A2SLC6A3SLC6A4 | |
| SCHEMBL6286943 | 0.83 | CYP2D6 (0.49) | CYP2D6KDM4EALDH1A1SLC6A3KMT2A | |
| SCHEMBL19336887 | 0.83 | CYP2D6 (0.63) | CYP2D6ALDH1A1SLC6A2SLC6A3SLC6A4 | |
| SCHEMBL7886071 | 0.83 | CYP2D6 (0.63) | CYP2D6ALDH1A1SLC6A2SLC6A3SLC6A4 | |
| SCHEMBL11265163 | 0.81 | CYP2D6 (0.62) | CYP2D6KDM4EALDH1A1SLC6A2SLC6A3 | |
| SCHEMBL6686361 | 0.80 | CYP2D6 (0.44) | CYP2D6KDM4EALDH1A1KMT2AGAA | |
| SCHEMBL17782589 | 0.80 | CYP2D6 (0.60) | CYP2D6KDM4EALDH1A1SLC6A2SLC6A3 | |
| SCHEMBL13465762 | 0.79 | CYP2D6 (0.71) | CYP2D6KDM4EALDH1A1SLC6A2SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7414145-B2 | Method of enantioselective nucleophilic addition reaction of enamide to carbonyl group and synthesis method of optically active α-hydroxy-γ-keto acid ester and hydroxydiketone | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2008-08-19 | — | — | US | disclosed |
| US-7414145-B2 | Method of enantioselective nucleophilic addition reaction of enamide to carbonyl group and synthesis method of optically active α-hydroxy-γ-keto acid ester and hydroxydiketone | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2008-08-19 | — | — | US | disclosed |
| US-20070073087-A1 | Method of enantioselective nucleophilic addition reaction of enamide to carbonyl group and synthesis method of optically active alpha-hydroxy-y-keto acid ester and hydroxydiketone | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2007-03-29 | — | — | US | disclosed |
| US-20070073087-A1 | Method of enantioselective nucleophilic addition reaction of enamide to carbonyl group and synthesis method of optically active alpha-hydroxy-y-keto acid ester and hydroxydiketone | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2007-03-29 | — | — | US | disclosed |
| US-20070073087-A1 | Method of enantioselective nucleophilic addition reaction of enamide to carbonyl group and synthesis method of optically active alpha-hydroxy-y-keto acid ester and hydroxydiketone | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2007-03-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070073087-A1 | Method of enantioselective nucleophilic addition reaction of enamide to carbonyl group and synthesis method of optically active alpha-hydroxy-y-keto acid ester and hydroxydiketone | HACL2, NAA15, HRH1 | CYP2D6 1306/4885KDM4E 1910/4885ALDH1A1 584/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.